Gut
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Gut microbiota metabolite protects against obesity: study
Vanderbilt researchers have discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity. Read MoreDecember 8, 2023
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Study discovers role for gut bacteria in host-pathogen competition for nutrients
Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and have implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients. Read MoreOctober 27, 2023
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Byndloss selected for Burroughs Wellcome Fund infectious disease award
Vanderbilt's Mariana Byndloss, DVM, PhD, is one of eight Burroughs Wellcome Fund 2023 Investigators in the Pathogenesis of Infectious Disease. Read MoreJune 7, 2023
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Host-microbe interactions in the gut
Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health. Read MoreAugust 13, 2019
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Lineage tracing in the gut
Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop. Read MoreNovember 30, 2017
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A DARPP role in gastric cancer
Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read MoreNovember 3, 2016
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Study identifies potential colon cancer biomarker
A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at Vanderbilt University Medical Center reported last month in the journal Gut. Read MoreFebruary 11, 2016
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Study sheds light on human gut’s ‘pacemaker’ cells
The gut has its own built-in pacemakers, populations of specialized cells that control smooth muscle contraction in the stomach, small intestine and colon. Read MoreJuly 30, 2015
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Nutrient-absorbing surface’s assembly revealed: study
Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens. Read MoreApril 17, 2014
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Defusing ‘C. diff’ infection
Clostridium difficile on the intestinal lining. (Wellcome Images) Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the… Read MoreNovember 8, 2013