GABA

Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability. Read More

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read More

Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy. Read More

Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy. Read More

Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures. Read More

Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex. Read More

Understanding how mutations in neuronal receptors contribute to epilepsy could lead to improved therapies. Read More

A new laser technique can measure interactions between proteins tangled in a cell's membrane and a variety of other biological molecules: extremely difficult measurements that can aid the process of drug discovery. Read More