Drug Repurposing
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VUMC’s program to repurpose drugs lands international acclaim
Vanderbilt University Medical Center is attracting international attention for its proposal to repurpose existing drugs for new uses in ways that can dramatically improve access to medicines by billions of people throughout the world. Read MoreJuly 23, 2020
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Vanderbilt University Medical Center among top 100 proposals for MacArthur Foundation $100 million grant
The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Change competition for a single $100 million grant to help solve one of the world’s most critical societal challenges. Read MoreFebruary 19, 2020
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Treating C. diff: new purpose for an old drug?
An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice. Read MoreSeptember 24, 2019
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Clinical study tests drug that may prevent cancer metastasis
A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center. Read MoreJuly 8, 2019
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Grant bolsters study of potential new therapy for C. diff infection
According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis. Read MoreMarch 22, 2018
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Study explores anti-viral potential of existing drugs
Emerging viral infections like Zika keep popping up around the world in such quick succession that medicine is having a hard time keeping up. It can take 15 years and more than a billion dollars to bring a new drug to market. Read MoreSeptember 15, 2016
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Initiative seeks to bolster ‘rediscovery research’
The Vanderbilt Institute for Clinical and Translational Research (VICTR) is partnering with a public charity, Cures Within Reach, to encourage “rediscovery research,” the “repurposing” of already approved medical treatments to other conditions or diseases for which there are no “universally” effective therapies. Read MoreSeptember 10, 2015
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Team finds drug repurposing signal in e-health records
With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increasing production. Read MoreNovember 20, 2014