DNA

Nashville Biosciences LLC and Illumina Inc. today announced an agreement with Amgen to whole-genome sequence approximately 35,000 DNA samples. Read More

Assistant Professor of Biochemistry Emily Hodges and graduate student Tyler Hansen used a blended approach to create a new, multi-omic method to identify and characterize gene regulatory elements—non-coding DNA sequences that control gene expression—in the human genome. Read More

by Paul Govern Information based biomedical discovery, in particular the push toward precision medicine, depends on open-ended analysis of de-identified data from patients and research participants on the largest possible scale. Sharing data while controlling the risk of data reidentification under privacy attack is vital to the enterprise. Zhiyu Wan Game theory indicates that only... Read More

After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works. Read More

Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read More

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis. Read More

When it comes to our differences from Neanderthals, most of what we know comes from comparing fossils. But fossils can only tell us about bones and not whole living organisms. That’s changing thanks to a new paper from a team of genomics researchers at Vanderbilt, who… Read More

David Cortez and colleagues have found that a protein called RADX helps modulate a protein called RAD51 in order to make sure exactly the correct amount of DNA repair occurs. Read More

Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases. Read More

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read More