David Cortez

Martin Egli, the Richard N. Armstrong, Ph.D. Professor of Innovation in Biochemistry and a professor of biochemistry at the School of Medicine Basic Sciences, delivered a Kairos Lecture on May 28. Egli’s work, which has resulted in over 300 publications and two influential nucleic acid textbooks, has advanced strategies to stabilize RNA for therapeutic applications, including siRNA. He has received major honors and extensively served his department and the university. Read More

David Cortez, a world-renowned leader in DNA damage response and repair mechanisms and the pathophysiology of cancer, developed and applied highly creative technological approaches to identify and characterize proteins involved in DNA and genome maintenance. The Protein Society is the premier international society dedicated to supporting protein research. Read More

After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works. Read More

Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA. Read More

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity. Read More

David Cortez and colleagues have discovered a new DNA repair mechanism. Read More

David Cortez and colleagues have found that a protein called RADX helps modulate a protein called RAD51 in order to make sure exactly the correct amount of DNA repair occurs. Read More

Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome. Read More

Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability. Read More

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports. Read More