Cell Reports

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells. Read More

Vanderbilt investigators and colleagues around the country have made a major discovery that could lead to better ways to treat type 1 diabetes (T1D). Read More

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read More

A protein that plays a powerful role in learning and memory may be a key to improving treatment of a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), a new study suggests. Read More

Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression. Read More

A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes. Read More

Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read More

A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.” Read More

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers. Read More

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Read More