Brain
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Research Snapshot: Protons can tune synaptic signaling by changing the shape of a protein receptor
Research from Teru Nakagawa, professor of molecular physiology and biophysics, describes intricacies of normal brain function with implications for our understanding of brain injury and recovery: A decrease in pH can modify a neurotransmitter receptor’s structure, thereby modulating its location and kinetics. Read MoreAugust 14, 2024
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VUMC scientists record powerful signal in the brain’s white matter
Vanderbilt researchers report that when people who are having their brains scanned by fMRI perform a task, like wiggling their fingers, certain signals increase in white matter throughout the brain, which has long been thought to play a lesser role the more the brain's more energetic gray matter. Read MoreOctober 16, 2023
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A connection to schizophrenia
The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found. Read MoreJune 23, 2020
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Team discovers one more piece to the autism puzzle
Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability. Read MoreOctober 3, 2019
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Astrocytes and epilepsy
A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report. Read MoreSeptember 9, 2019
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MRI technique detects spinal cord changes in MS patients: study
A Vanderbilt University Medical Center-led research team has shown that magnetic resonance imaging (MRI) can detect changes in resting-state spinal cord function in patients with multiple sclerosis (MS). Read MoreApril 19, 2018
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Sorry, Grumpy Cat—Study finds dogs are brainier than cats
The first study to actually count the number of cortical neurons in the brains of a number of carnivores, including cats and dogs, has found that dogs possess significantly more of them than cats. Read MoreNovember 29, 2017
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‘Mind’s eye blink’ proves ‘paying attention’ is not just a figure of speech
Vanderbilt psychologists have discovered that when you shift your attention from one place to another, your brain 'blinks'—or experiences momentary gaps in perception. Read MoreNovember 21, 2017
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Regulating anxiety in the brain
Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both. Read MoreApril 28, 2017
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Protecting the blood-brain barrier
Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers. Read MoreDecember 9, 2016