Biomedical Engineering
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Nanoparticles boost anti-cancer immunity
by Bill Snyder The growth of epithelial ovarian cancer, one of the most lethal malignancies, is associated with the presence of tumor-associated macrophages (TAMs), white blood cells that can block the anti-cancer activity of the immune system and immunotherapy. Fortunately, TAMs can be “repolarized,” converted from immunosuppressive tumor-promoters to inflammatory tumor-fighters. Now, Associate Professor of Pharmacology Fiona Yull,... Read MoreAugust 16, 2022
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Three engineering faculty win Vanderbilt grants to support early-stage pioneering research
Three engineering faculty members have received grants to support the early stages of pioneering research projects identified as likely candidates for further funding from federal, foundation and industry sponsors. Spring 2022 Seeding Success Grants were awarded to 14 faculty and are the second cycle of the internal early investment funding initiative. The grants, awarded to faculty spanning the... Read MoreJune 29, 2022
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International collaboration reveals how the human brain evolved to harness abstract thought
By Marissa Shapiro THE IDEA The human brain is organized in functional networks—connected brain regions that communicate with each other through dedicated pathways. That is how we perceive our senses, how the body moves, how we are able to remember the past and plan for the future. The “default mode” network is the part of... Read MoreApril 12, 2022
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Study finds 10-second videos predict blood cancer relapse
Biomedical engineering prof says study raises the prospect of a new application of diagnostic optical biopsy by Paul Govern In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse... Read MoreApril 4, 2022
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Rubinov awarded $1.1M to study molecular underpinnings of human brain networks on a large scale
Mikail Rubinov, assistant professor of biomedical engineering, computer science, psychiatry and psychology, has been awarded a four-year, $1.1 million grant from the National Institute of Mental Health to better understand the development and organization of brain networks, as well as their change in development and aging. Rubinov and his collaborators will link aspects of gene expression and... Read MoreMarch 17, 2022
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Wikswo, VIIBRE team on track to build third-generation ‘self-driving lab’ with $1M from NSF
John Wikswo, founder and director of the Vanderbilt Institute for Integrative Biosystems Research and Education and Gordon A. Cain University Professor, is the principal investigator of a $1 million award from the National Science Foundation. The object is to build a pathbreaking “robot scientist”—a fully automated microfluidic system for parallel, independent, long-duration, machine-guided experiments. The... Read MoreMarch 5, 2022
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Multicenter team seeks to create at-home artificial lung system
Vanderbilt team to focus on engineering, testing the device by Matt Batcheldor Vanderbilt University Medical Center will share in an $8.7 million federal grant to create an artificial lung system that patients with incurable lung disease can use at home. The Department of Defense Congressionally Directed Medical Research Program (CDMRP) grant will fund research to create... Read MoreFebruary 24, 2022
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Autoimmune drug shows promise in treating severe burns
A severe burn injury is not static. Within 72 hours, partial thickness burns can progress, or convert, to full thickness burns, greatly increasing the risk of infection, incapacitating scarring, and even death. Preventing the conversion is one of the most challenging aspects of treating burns, and a trans-institutional team of researchers from Vanderbilt University Medical... Read MoreJanuary 12, 2022
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Headband device suitable for use at home with young ADHD patients
Vanderbilt biomedical engineering professor has developed a prototype headband to measure brain activity that could have widespread application in studying and ultimately treating ADHD and other neurological disorders. The device is lightweight, portable, and inexpensive to construct. Prototype components cost less than $250, compared to costs exceeding $10,000 for commercial systems. Audrey Bowden, associate professor... Read MoreNovember 16, 2021
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New drug targets vascular inflammation, drastically improves vascular procedures’ long-term effectiveness
By Aran Sullivan THE IDEA Cardiovascular procedures like bypass grafting and vessel stenting are some of the most common surgeries performed in the United States, but about half of them will require additional corrective measures, according to Craig Duvall, Cornelius Vanderbilt Chair and undergraduate director of biomedical engineering. The need for follow-up procedures is often... Read MoreOctober 12, 2021