Aging

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic “map” of how cells orchestrate glucose processing, revealing a hidden world where organelles and molecular complexes collaborate when responding to a rush of nutrients. This new study, published in Nature Communications, has redefined how glucose metabolism is visualized at the single-cell level. Read More

New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output. Read More

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis. Read More

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity. Read More

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered. Read More

A genetic risk factor for Alzheimer’s disease in later life appears to benefit younger adults as they age. Read More

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read More

Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel. Read More

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets. Read More

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold. Read More