Jennifer M. Noto

Regulation of Pro-Inflammatory Phenotypes by Carcinogenic and Non-Carcinogenic Helicobacter pylori strains

In order to quantify H. pylori virulence, the concentration of IL-8 secreted by AGS gastric epithelial cells co-culture with H. pylori strains, isolated from patients with gastritis or gastric adenocarcinoma was measured and compared.
Identification of Novel Helicobacter pylori Adhesins that Bind the Host Cell Receptor Decay-Accelerating Factor (DAF)

H. pylori adherence is critical for gastric cancer development, and this study has identifi ed novel adhesins responsible for DAF-mediated adherence.