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Frederick R. Haselton

Professor of Biomedical Engineering
Professor of Ophthalmology and Visual Sciences
Professor of Chemistry

Research:

Much of my personal motivation for working in biomedical engineering derives from my interest in dreaming up new technologies or devices to directly impact health and our understanding of the underlying cellular and molecular phenomena. My laboratory has made contributions in many diverse areas from fluid mechanics of high frequency ventilation used with premature infants to optically activated gene expression for delivering targeted genetic therapies. Many of our current lab projects involve the application of unusual physical properties at the micro and nanoscale to develop novel diagnostic tools. I am particularly excited our recent progress in developing simple diagnostic tools based on the science underlying phenomena as diverse as the optical properties of quantum dots and the microfluidics of the coffee ring phenomenon. With further development, these technologies offer to deliver new diagnostic tools to a greater fraction of the world’s population.

Awards:

Fellow, AIMBE

Selected Publications:

A two-magnet strategy for improved mixing and capture from biofluids. Scherr, TF; Ryskoski, HB; Doyle, AB; Haselton, FR, BIOMICROFLUIDICS, 10, 024118 , (2016) View Abstract

Comparison of Three Magnetic Bead Surface Functionalities for RNA Extraction and Detection. Adams, NM; Bordelon, H; Wang, KKA; Albert, LE; Wright, DW; Haselton, FR, ACS APPLIED MATERIALS & INTERFACES, 7, 6062-6069 , (2015) View Abstract

Tuberculosis Biomarker Extraction and Isothermal Amplification in an Integrated Diagnostic Device. Creecy, A; Russ, PK; Solinas, F; Wright, DW; Haselton, FR, PLOS ONE, 10, e0130260 , (2015) View Abstract

Biosensor design based on Marangoni flow in an evaporating drop. Trantum, JR; Baglia, ML; Eagleton, ZE; Mernaugh, RL; Haselton, FR, LAB ON A CHIP, 14, 315-324 , (2014) View Abstract

Coffee Rings as Low-Resource Diagnostics: Detection of the Malaria Biomarker Plasmodium falciparum Histidine-Rich Protein-II Using a Surface-Coupled Ring of Ni(II)NTA Gold-Plated Polystyrene Particles. Gulka, CP; Swartz, JD; Trantum, JR; Davis, KM; Peak, CM; Denton, AJ; Haselton, FR; Wright, DW, ACS APPLIED MATERIALS & INTERFACES, 6, 6257-6263 , (2014) View Abstract