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David E. Cliffel

Cornelius Vanderbilt Chair
Professor of Chemistry
Professor of Physics and Astronomy
Associate Professor of Pediatrics


Multianalyte Microphysiometry for Organs on a Chip 
Analytical chemistry often leads the forefront of scientific discovery, as new instrumentation allows us to perform new experiments. Our group has created multianalyte microphysiometry by combining microfluidic technologies with electrochemical detection to study the dynamic behaviors of metabolic pathways. We are developing new multianalyte microphysiometry methods with applications in cancer, diabetes, and toxicology. We have added electrochemical detectors for many metabolic analytes into the microfluidic chamber to give a complete dynamical picture of the live cell populations including organ on a chip platforms.

Electrochemistry on the Nanoscale 
Electron transfer in nanometer-size chemical systems is an important process for the creation of macromolecular electronics. We are interested in the electrochemistry of metallic nanoparticles, redox proteins like Photosystem I, and other electroactive nanomaterials that bridge the gap between bulk solids and discrete molecules in the development of electronic devices using nanotechnology.


-Society of Electroanalytical Chemistry (SEAC) Young Investigator Award, 2005
-ACS Younger Chemistry Committee Leadership Development Award, 2004
-Central Texas ACS Local Section Appreciation Award, 1997
-Federation of Analytical Chemistry and Spectroscopy Societies Student Award, 1995
-Hoechst Celanese Excellence Awards in Chemistry, Top UT Chemistry Graduate Student Award, 1995
-George Geisler Excellence Award in Chemistry, University of Dayton, 1992
-Thomas Armstrong Outstanding Electrical Engineering Achievement Award, University of Dayton, 1992
-Horvath/ Steger Excellence Award in Electrical Engineering, University of Dayton, 1992
-ACS Undergraduate Analytical Chemistry Award, 1991
-Patterson College Chemistry Award from the Dayton ACS local section, 1991
-Louis Rose Award- Outstanding Electrical Engineer Junior, University of Dayton, 1990
-John Lucier Award- Outstanding Chemistry Junior, University of Dayton, 1990
-Silver Medal at the 20th International Chemistry Olympiad in Helsinki, Finland, 1988