Vanderbilt Institute of Chemical Biology



Ways to give to
the VICB












Medical research doesn’t usually result in immediate cures; instead, the process is incremental and often slow. But over a period of years, progress can be impressive. Consider, for example, the 56% reduction in death from heart disease since 1950 due to a combination of drugs to control blood pressure and cholesterol, dietary interventions, reductions in smoking, and improved surgical treatments. All of these advances began with basic research into the causes of heart disease and the best ways to prevent or reverse their deadly effects. Indeed, without basic research all medical advances would come to a grinding halt.







The incubator


The VICB serves as a highly efficient incubator of basic medical research at Vanderbilt. Examples of projects currently being pursued by VICB investigators are:



  • the discovery of new potential anti-tumor agents that block the function of RPA70N, a protein that promotes the growth and survival of some kinds of cancer cells.
    Stephen Fesik, David Cortez, and Walter Chazin

  • the discovery that agents closely related to nonsteroidal anti-inflammatory drugs (such as aspirin, ibuprofen, and naproxen) may be useful in the treatment of anxiety.
    Larry Marnett and Sachin Patel

  • the identification of molecules that inhibit an enzyme known as PLD (phospholipase D). These agents have promising anti-tumor activity against glioblastoma multiforme, a particularly aggressive form of brain cancer.
    Alex Brown and Craig Lindsley

  • the discovery of molecules that block the function of a protein that transports potassium ions across cell membranes. Their anti-seizure activity in mice, suggests a possible new approach for the treatment of epilepsy.
    Jerod Denton and David Weaver

  • the creation of a molecule that can be used with PET (positron emission tomography) imaging to detect cells undergoing a form of cell death. This imaging agent may be used to monitor the response of cancer to therapy.
    Charles Manning

  • the discovery of molecules that activate proteins involved in olfaction (the sense of smell) in mosquitoes. These molecules may serve as a very effective mosquito repellant that could both fend off an irritating pest and be used to control malaria, a devastating disease in the developing world.
    Larry Zwiebel

  • the identification of new molecules that are toxic to bacteria growing under low oxygen conditions. These compounds are being investigated as potential new drugs to treat antibiotic-resistant bacterial infections.
    Eric Skaar and Gary Sulikowski

  • the development of new, highly innovative diagnostic tests for malaria. Their devices, which can be used easily in the field allows asymptomatic carriers to be identified and treated, so they do not serve as a source for further spread of the malaria parasite.
    David Wright and Rick Haselton




VICB researchers such as these have been highly successful in obtaining funding for their research. However, maintaining the environment that supports their work also requires money that cannot easily be obtained through typical grant applications. Your support will help to keep the VICB strong, so that these and other vital research programs will continue to thrive.

Contact Development
and Alumni Relations


Vanderbilt University Medical Center

Development and Alumni Relations

2525 West End Ave., Suite 450

Nashville, TN 37203

Local: (615) 936-0230

Free: (800) 288-0028

Fax: (615) 936-7425



Philanthropic support is critical for pushing the frontier of chemical biology and advancing promising leads to the clinic. We have the potential to make fundamental breakthroughs of new therapies that impact people here and around the world, but we need your help.



Make a gift online here


The" Vanderbilt Institute for Chemical Biology" fund name will automatically appear under “Allocation Description."




or mail in your gift.

Make checks payable to Vanderbilt Institute for Chemical Biology and mail it to:

Vanderbilt Institute for Chemical Biology
c/o Gift Processing
PMB 407727
2301 Vanderbilt Place
Nashville, TN 37240-7727


Tribute gifts

Honor someone special, a special occasion or the memory of a loved one or friend by making a gift to Vanderbilt University Medical Center in their name. For more information about tribute giving, call (615) 936-0230.


Make a tribute gift online now.

Please indicate the name of the name and contact information of the person you are honoring. We will then notify the recipient of your generosity.




Other ways to give


  • Planned Giving

  • Stocks and Securities


Gifts large and small keep Vanderbilt on the leading edge of world-class health care and discovery.Learn more about giving to Vanderbilt University Medical Center.




The Vanderbilt Institute of Chemical Biology, 896 Preston Building, Nashville, TN 37232-6304, phone 866.303 VICB (8422), fax 615 936 3884
Vanderbilt University is committed to principles of equal opportunity and affirmative action. Copyright © 2014 by Vanderbilt University Medical Center

  • Areas of Interest