The Yull lab is seeking a postdoctoral fellow who is interested in the potential for modulating macrophage behavior as a cancer therapy. We use mouse models of breast metastasis to lungs and bone and of ovarian cancer as we investigate novel therapeutic approaches for these diseases.
Pharmacology | |
We are seeking a postdoctoral fellow to work on a recently funded collaborative project. The studies will include the Yull lab (mouse models and NF-kappaB), the lab of Julie Rhoades (expert in bone biology) and the lab of Todd Giorgio (expert in nanoparticle development and biomedical engineering). The Yull and Giorgio labs have been working together for more than 10 years with co-authored publications, jointly mentored trainees and multiple shared research awards. These are exciting studies that will use multiple methods to modulate Nuclear Factor-kappaB signaling specifically in macrophages to develop new options for treatment of breast metastases in the lungs or bone. Mouse models of metastases will be used to evaluate treatment approaches including doxycycline-inducible transgenic mice, liposomal drugs and or nanoparticle delivery of siRNA to macrophages. Previous experience that would be of value includes; use of mouse models of cancer (particularly in lung and/or bone), flow cytometry, IHC and/or IF, qRT-PCR, cell culture, protein analysis and basic lab skills. Strong communication and social skills and the ability to function with a high level of independence but to mentor junior lab members as needed would be considered a plus. |
|
Interested individuals should contact Dr. Yull at Fiona.Yull@vanderbilt.edu for more information/conversation and submit a current CV with the inclusion of 3 references. |
|
Fiona Yull : fiona.yull@vanderbilt.edu : (615) 343-2568 |
|
2022-10-06 20:39:24 |