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Position Detail

Postdoctoral research position to study the molecular and structural basis for mitochondrial DNA (mtDNA) maintenance


The Brown lab focuses on using structural biology to understand how defects in macromolecular protein assembly underlie mitochondrial diseases. Specifically, we are recruiting for a postdoc to study protein assembly interactions governing maintenance of mitochondrial DNA copy number through adequate dNTP production. In addition to structural biology, the laboratory also employs a wide range of biochemical and biophysical techniques to discern molecular mechanisms, including mass spectrometry, enzyme assays, and various binding assays. Successful applicants will have a foundation in structural biology (X-ray crystallography, NMR, cryo-EM) with further opportunities for cell biology, proteomics, and metabolomics.

Members of the laboratory will be based in the renovated Biochemistry Department space and will work in a collaborative and interactive community space shared with several other biochemistry laboratories.

For more information, please visit the Brown Laboratory website.

To apply, please send a cover letter, CV, and names and contact information for three references to Breann Brown.

Breann Brown, PhD
: (615) 343-1632
2020-07-22 16:28:56

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