The basic Cardio-Oncology group at Vanderbilt and the Moslehi Laboratory are seeking a highly motivated candidate to be a postdoctoral fellow in the Division of Cardiovascular Medicine and the Cardio-Oncology Program.
Medicine, Cardiology, Cancer Biology
The basic Cardio-Oncology group at Vanderbilt and the Moslehi Laboratory are seeking a highly motivated candidate to be a Post-Doctoral Fellow in the Division of Cardiovascular Medicine and the Cardio-Oncology Program. The successful applicant will hold a Ph.D. and/or M.D. with experience in molecular biology, biochemistry and animal models. Ability to work independently and cooperatively within a team of clinicians and scientists is essential. Salary is dependent upon the applicant’s experience and follows NIH guidelines.
This position is specifically tailored to an applicant with a strong immunology background. The Moslehi laboratory has an interest in fundamental interactions between the immune and cardiovascular systems. This interest has been partly motivated by the laboratory’s previous work in identifying clinical syndromes of immune-checkpoint inhibitor (ICI)-associated cardiovascular toxicities which include myocarditis, pericarditis and vasculitis (Johnson et al, NEJM, 2016. Moslehi et al, Lancet, 2018. Salem et al, Lancet Oncology, 2018). We have created pre-clinical models for ICI-associated myocarditis including pharmacologically-treated and genetic mouse models. The preliminary data from the laboratory suggest a critical role of immune checkpoint (specifically PD-1 and PD-L1) in the cardiac homeostasis and human cardiovascular disease, a hypothesis that is currently being tested in the laboratory.
PhD in genetics, molecular biology, cell biology, immunology, or related field.
Skills in molecular biology techniques including single cell RNA sequencing, data analysis.
Enthusiastic, self-motivated, and able to actively lead complex translational projects.
Excellent written and oral communication skills.
About Vanderbilt Cardio-Oncology program The Vanderbilt cardio-oncology program is interested in the intersection of cardiovascular medicine and oncology and integrates basic and translational scientists and clinicians. It is the premier such program in the world.
About Vanderbilt University Medical Center (VUMC) Vanderbilt University School of Medicine is a top ranked medical school and is equipped with world-class cutting-edge experimental and computational core facilities. As a postdoc, you have access to additional training and resources through the BRET office.
About Nashville Nashville is a vibrant and growing city, which offers high quality music, great restaurants, rapid access to outdoor activities and is centrally located within the US