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Position Detail

Postdoctoral position in membrane biology with relevance to diet-induced obesity, type 2 diabetes and heart disease.

Biological Sciences

An NIH-funded postdoctoral position is available in the Graham laboratory to study mechanisms of membrane biogenesis in eukaryotic cells. Current studies focus on how and why type IV P-type ATPases (P4-ATPases) recognize and transport their phospholipid substrate across membrane bilayers. We mutationally tune the substrate specificity of P4-ATPase and define the physiological consequences of the resulting membrane perturbation in systems ranging from budding yeast, human cell lines and genome-edited mice. P4-ATPase deficiency is linked to a number of diseases, including type 2 diabetes, heart disease, liver disease and neurodegenerative diseases. An important goal is to understand the molecular basis for these disease associations.

Candidates should send a CV and cover letter including contact information for at least three references to Todd Graham.

Todd Graham, PhD
: (615) 343-1835
2018-09-24 13:07:51

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