Vanderbilt University
Vanderbilt Institute of Chemical Biology
High Throughput Screening Facility


authorship and acknowledegment guidelines

As you near publishing work that used HTS resources, please consider the following:

Some of the projects that we support require significant intellectual input from HTS research faculty and staff in a way to warrant co-authorship on publications and listing as co-PI on grants. Examples include contributing to the design and development of an assay and determining the approach for and carrying out data analysis.

We request that the recommendations for authorship of the International Committee of Medical Journal Editors (ICMJE) be followed and that the PI engages HTS collaborators during the project and manuscript preparation. According to the ICMJE recommendations, individuals who meet all of the following criteria should be included as co-authors:

· Substantial contributions to the conception or design of the work; or the acquisition,   analysis, or interpretation of data for the work; AND
· Drafting the work or revising it critically for important intellectual content; AND
· Final approval of the version to be published; AND
· Agreement to be accountable for all aspects of the work in ensuring that questions   related to the accuracy or integrity of any part of the work are appropriately
  investigated and resolved.

Depending on the resource(s) that you use within HTS (including Compound Management and Informatics), a general or more specific acknowledgment may be appropriate. Below are examples of acknowledgements to include.

Resource Example Acknowledgement
HTS Core Experiments were performed in the Vanderbilt High-throughput Screening Core Facility which is an institutionally supported core with assistance provided by <staff member names>.
Seahorse Analyzer The Seahorse Biosciences Extracellular Flux Analyzer is housed and managed within the Vanderbilt High-throughput Screening Core Facility, an institutionally supported core, and was funded by NIH Shared Instrumentation Grant 1S10OD018015.
NIH Clnical
Collection Small Molecule LIbrary
The NIH Clinical Collection is provided through the National Institutes of Health Molecular Libraries Roadmap Initiative and was distributed by the Vanderbilt High-throughput Screening Core Facility, an institutionally supported core.
Other Small
Molecule Libraries
The <collection name> was distributed by the Vanderbilt High-throughput Screening Core Facility, an institutionally supported core.

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Lab Policy

Please see our FAQs.

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Administrative Policy

Completion of a High Throughput Screening Facility Intake Form or New Account or Training Form signifies agreement for service and supply fees associated with the project to be charged to the selected center number through the CORES system. These fees may include, but are not limited to, equipment use, labor (services), training, data analysis and supply costs. Our fees are directly charged to the selected center number through the CORES system on a monthly basis. Please note that users may return to this site at any time and change the default center number by completing the Center Number Update Form. In addition, as a CORES user, changing the center number for an individual charge can be made while making a reservation. A Principal Investigator or Administrative Officer can change a center number until the closing date of the month, through the CORES system site under Center Number Correction/Distribution.

Maintaining an active default center number is the responsibility of the user. Should a center number expire, it must be updated in the HTS system before any services or reservations are made for the month. All charges against closed center numbers are the responsibility of the user and must be corrected with a journal entry within the department.

All users requesting the use of scholarship funds must also provide an active center number. The scholarship number will be used for all reservations and labor in accordance with the scholarship details. However, scholarships may not be used for supplies or orders through e-procurement. For this reason, an active center number is required before HTS services begin.

The HTS staff endeavors to achieve success with all projects and will thoroughly assess projects at each step of the screening process. As with all research, success cannot be guaranteed. Please be aware that users will be billed for all services, supplies, and equipment time regardless of assay success. A quote may be requested before beginning work on a project to estimate costs for HTS services, supplies, and equipment use as described during the intake process. Due to the variability of assays and cell conditions, please allow for 15% variance in costs from the quote. If the work should require further changes, HTS will contact the PI/users before proceeding.

In addition, users will be required to agree to adhere to all HTS policies and procedures outlined in the training sessions with regard to equipment usage and to all HTS Facility Safety Policy guidelines. Failure to follow these policies and procedures may result in charges for equipment repair and/or require additional training. Repeated failure to comply with HTS Facility Policies may result in loss of access to HTS services and equipment.

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Safety and Emergency Policy

Please view Vanderbilt's Environmental Health & Safety "Basics of Biosafety Level 2".

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Data Sharing Policy

The HTS Core Facility Stores project Data on network drives which are routinely backed up. Raw data is stored to a Data Drive in an anonymous, unlinked format. Data analysis information and protocols will be stored on Sharepoint for each project. By default, all project level information on the project site is private. The PI for each project, or a designated proxy, will be able to add user access to the project site for additional lab members and collaborators. HTS staff members will have access to all project data for the purposes of quality control. PIs have the option of sharing their target, compound hits, or other data with other PIs with compatible interests and assays. PIs must opt-in for any sharing options when completing the Intake Form. All data acquired in the HTS facility, data analysis performed by HTS staff, or protocols and assays developed by HTS staff must be acknowledged in any publication, presentations, and grant applications resulting from the work.

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