Research Spotlight: Hassane Mchaourab

Posted by daviskd2 on Wednesday, February 26, 2020 in News.

CSB Researcher Hassane Mchaourab and his lab pinpointed the role of an amino acid residue – a glutamate – that is essential for proton sensing & drug resistance. Using a proton gradient, PfMATE undergoes a structural change to allow its substrates to enter through the cytoplasm & get released outside the cell. Read the PNAS article.