Ewa received her B.S. in Forensic Science from the University of Northumbria in England which involved a year in industry working for a pharmaceutical services company. She pursed an undergraduate research thesis under the supervision of Dr. Justin Perry studying the sources of yellow natural yellow dyes used in historical objects with liquid chromatography mass spectrometry. Samples included dyes taken from works of art Reclining Tiger by Jean-Baptiste Oudry and the 1893 version of The Scream by Edvard Munch. Ewa completed her Ph.D. in Biophysical Chemistry in the School of Chemistry at University of Edinburgh in Scotland under the guidance of Prof. Perdita E. Barran. Her research in the Barran group investigated the effects of different drift gases on protein ions using ion mobility mass spectrometry, as well as exploring the use of IM-MS to examine intrinsic disorder in proteins. She assessed the dynamic conformational architecture and thermal stability of the cellular tumour antigen p53 and its E3 ubiquitin ligase Mdm2. In collaboration with Dr Penka Nikolova (King’s College London, UK) she interrogated the tumorigenic mutations which occur in the core domain of p53, as well the protein - DNA interactions. Additionally, she was also involved in work in collaboration with Prof Collin Creaser (Loughborough University, UK) investigating the use of mobility standards in IM-MS. Ewa has joined Prof. John McLean’s laboratory in April 2014 as a postdoctoral research fellow where she is developing expertise in instrument building for the structural mass spectrometry filed. Her current projects include the development of a cryogenic ion mobility mass spectrometer for high resolution measurements as well as work on the Agilent prototype drift-tube ion mobility mass spectrometer.

Publications:

Ewa Jurneczko , Faye Cruickshank, Penka V. Nikolova, Iain D. G. Campuzano, Michael Morris, Perdita E. Barran., ‘Probing the Conformational Diversity of p53 Cancer-associated Mutations by Ion Mobility-Mass Spectrometry’. Angewandte Chemie International Edition, published as a ‘hot topic article’ 2013, 52 (16), 4370-4374.

Victoria E. Wright, Fernando Castro-Gómez, Ewa Jurneczko, James C. Reynolds, Andrew Poulton, Steven D. R. Christie, Perdita Barran, Carles Bo, Colin S. Creaser., ‘Structural Studies of Metal Ligand Complexes by Ion Mobility-Mass Spectrometry’. International Journal of Ion mobility Spectrometry, 2013, 16 (1), 61-67

Ewa Jurneczko, Jason Kalapothakis, Iain D. G. Campuzano, Michael Morris, and Perdita E Barran., ‘The Effects of Drift Gas on Collision Cross-Sections of a Protein Standard in Linear Drift Tube and Travelling Wave Ion Mobility Mass Spectrometry’. Analytical Chemistry 2012, 84 (20), 8524-8531

Ewa Jurneczko , Faye Cruickshank, Massimiliano Porrini, Penka Nikolova, Iain D. G. Campuzano, Michael Morris, Perdita E. Barran., ‘Intrinsic Disorder in Proteins: A Challenge for (Un)structural Biology met by Ion Mobility-Mass Spectrometry’. Biochemical Society Transactions 2012, 40 (5), 1021-1026. Ewa Jurneczko and Perdita E. Barran., ‘How useful is Ion Mobility Mass Spectrometry for Structural Biology? The Relationship between Protein Crystal Structures and their Collision Cross Sections in the Gas Phase. Analyst 2011,136, 20-28

Justin J. Perry, Lauren Brown, Ewa Jurneczko, Edwin Ludkin and Brian Singer., ‘Identifying the Plant Origin of Artists' Yellow Lake Pigments by Electrospray Mass Spectrometry. Archaeometry, 2010, 53 (1), 164-177