All Contents Copyrighted 2014

Zwiebel Lab Publications

(Please click on title for link to article/abstract; *denotes equal contributions)


 

2014:


Antennal-Expressed Ammonium Transporters in the Malaria Vector Mosquito Anopheles gambiae.

R. Jason Pitts*, Stephen Derryberry*, Fadi Pulous and Laurence J. Zwiebel, PLoS ONE, in press.


Divergent and conserved elements comprise the chemoreceptive repertoire of the non-blood feeding mosquito Toxorhynchites amboinensis
Xiaofan Zhou*, David C. Rinker*,  R. Jason Pitts, Antonis Rokas and Laurence J Zwiebel.  Genome Biology and Evolution 2014;  doi: 10.1093/gbe/evu231


Mutational Analysis of Cysteine Residues of the insect Odorant Co-receptor (Orco) from Drosophila melanogaster Reveals Differential Effects on Agonist- and Odorant/tuning Receptor-Dependent Activation.

Rebecca M. Turner, Stephen Derryberry, Brijesh N. Kumar, Thomas Brittain, Laurence J. Zwiebel, Richard D. Newcomb and David L. Christie, Journal of Biological Chemistry,  jbc.M114.603993. First Published on September 30, 2014, doi:10.1074/jbc.M114.603993.



A Determinant of Odorant Specificity is Located at the Extracellular Loop 2 - Transmembrane Domain 4 Interface of an Anopheles gambiae Odorant Receptor Subunit.

David T. Hughes, Guirong Wang, Laurence J. Zwiebel and Charles W. Luetje, Chemical Senses, 2014;

doi: 10.1093/chemse/bju048.


The Future of Insect Repellent Discovery and Development.

Jonathan D. Bohbot, Daniel Strickman and Laurence J. Zwiebel, Outlooks on Pest Management, August 2014 25(4): 265-270.


Narrow Structure Activity Relationships in Odorant Sensing Orco Receptor Agonists.

Ian M. Romaine, Robert W. Taylor, Samsudeen P. Saidu, Gary A. Sulikoski, Laurence J. Zwiebel and Alex G. Waterson, Bioorganic and Medicinal Chemistry Letters, (2014) Apr 29. pii: S0960-894X(14)00438-7. doi: 10.1016/j.bmcl.2014.04.081. Epub 2014 May10.


Odorant Receptor-Mediated Sperm Activation in Disease Vector Mosquitoes.

R. Jason Pitts*, Chao Liu*, Xiaofan Zhou*, Juan C. Malpartida and Laurence J Zwiebel, Proceedings of the National Academy of Sciences USA (2014) 111 (7) 2566-2571, doi:10.1073/pnas.1322923111, Epub 2014 Feb 3.


2013:


Antennal transcriptome profiles of anopheline mosquitoes reveal human host olfactory specialization in Anopheles gambiae

David Rinker, Xiaofan Zhou, R. Jason Pitts, Antonis Rokas and Laurence J Zwiebel, BMC Genomics, 2013, 14:749. doi:10.1186/1471-2164-14-749. Epub 2013 Nov 1.


A Conserved Aspartic Acid Is Important for Agonist (VUAA1) and Odorant/Tuning Receptor-Dependent Activation of the Insect Odorant Co-Receptor (Orco)

Brijesh N. Kumar, Robert W. Taylor, Gregory M. Pask, Laurence  J. Zwiebel, Richard D. Newcomb and David L. Christie, PLoS ONE, published 23 Jul 2013 | PLOS ONE 10.1371/journal.pone.0070218.


Molecular Characterization of Larval Peripheral Thermosensory Responses of the Malaria Vector Mosquito Anopheles gambiae.

Chao Liu and Laurence J. Zwiebel, PLoS ONE, published 07 Aug 2013 | PLOS ONE 10.1371/journal.pone.00725.


Blood Meal-Induced Changes to Antennal Transcriptome Profiles Reveal Shifts In Odor Sensitivities in Anopheles gambiae

David C Rinker, Ronald Jason Pitts, Xiaofan Zhou, Eunho Suh, Antonis Rokas and Laurence J. Zwiebel,

Proceedings of the National Academy of Sciences USA (2013) 110 (20): 8260-8265, doi:10.1073/pnas.1302562110 Epub 2013 Apr 29.


Blockade of Insect Odorant Receptor Currents by Amiloride Derivatives 

Gregory M. Pask; Yuriy V. Bobkov; Elizabeth A. Corey; Barry W. Ache; Laurence J. Zwiebel

Chemical Senses 2013 38 (3): 221-229; doi: 10.1093/chemse/bjs100



2012:


The Molecular Receptive Range of an Enantio-selective Lactone Receptor in Anopheles gambiae. 

Gregory M. Pask, Ian M. Romaine and Laurence J. Zwiebel

Chemical Senses (2012) first published online September 2, 2012 doi:10.1093/chemse/bjs074


Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals caste-specific signatures of odor coding

Xiaofan Zhou*, Jesse D Slone*, Antonis Rokas, Shelley Berger, Jürgen Liebig, Anandaskar Ray, Danny Reinberg, and Laurence J. Zwiebel

PLoS Genetics 8(8): e1002930. doi:10.1371/journal.pgen.1002930

 

 

Structure-Activity Relationship of a Broad-Spectrum Insect Odorant Receptor Agonist.

Robert W. Taylor*, Ian M. Romaine*, Chao Liu, Poornima Murthi, Patrick L. Jones, Alex G. Waterson, Gary A. Sulikowski and Laurence J. Zwiebel

ACS Chemical Biology, Article ASAP, doi:10.1021/cb300331z


Spatial repellents: from discovery and development to evidence-based validation.

Nicole L Achee, Michael J Bangs, Robert Farlow, Gerry F Killeen, SteveLindsay, James G Logan, Sarah J Moore, Mark Rowland, Kevin Sweeney, Steven J Torr, Laurence J. Zwiebel and John P Grieco

Malaria Journal (2012) 11: 164 doi:10.1186/1475-2875-11-164.


Novel high-throughput screens of Anopheles gambiae odourant receptors reveal candidate behaviour-modifying chemicals for mosquitoes.

David C. Rinker*, Patrick l. Jones*, R. Jason Pitts, Michael Rützler, J. Gray Camp, Lujuan Sun, Pingxi Xu, Daniel Dorset, David Weaver and Laurence J. Zwiebel

Physiological Entomology (2012) 37, 33-41


Allosteric Antagonism of Insect Odorant Receptor Ion Channels.

Patrick L. Jones, Gregory M. Pask, Ian M. Romaine, Robert W. Taylor, Paul R. Reid, Alex G. Waterson, Gary A. Sulikowski, Laurence J. Zwiebel

PLoS ONE 7(1): e30304. doi:10.1371/journal.pone.0030304



2011:


Heteromeric Anopheline Odorant Receptors Exhibit Distinct Channel Properties.

Gregory M. Pask, Patrick L. Jones, Michael Rützler, David Rinker and Laurence J. Zwiebel

PLoS ONE, 6(12): e28774. doi:10.1371/journal.pone.0028774.


Transcriptome profiling of chemosensory appendages in the malaria vector Anopheles gambiae reveals tissue- and sex-specific signatures of odor coding.

R. Jason Pitts*, David C. Rinker*, Patrick L. Jones*, Antonis Rokas and Laurence J. Zwiebel

BMC Genomics. 2011 May 27;12:271. doi: 10.1186/1471-2164-12-271


Functional Agonism of Insect Odorant Receptor Ion Channels.

Patrick L. Jones*, Gregory M. Pask*, David Rinker and Laurence J. Zwiebel

Proceedings of the National Academy of Sciences USA,  2011 May 24, 108 (21): 8821-8825 published ahead of print May 9, 2011, doi:10.1073/pnas.1102425108.


Conservation of Indole Responsive Odorant Receptors in Mosquitoes Reveals an Ancient Olfactory Trait.

Bohbot, JD*, Jones, PL*, Wang, G*. Pitts. RJ, Pask, GM and LJ Zwiebel

Chemical Senses (2011) Jan;36(2): 149-60. Epub 2010 Oct 18.


A Research Agenda for Malaria Eradication: Vector Control. The MalERA Consultative Group on Vector Control (13 authors including LJ Zwiebel).

PLoS Medicine (2011) 8(1):e1000401 doi:10.1371/ journal pmed.10041.

Functional Characterization of pheromone receptors in the tobacco budworm Heliothis virescens.

Wang. G., Vasquez, G., Schal, C., Zwiebel, L.J., and Fred Gould

Insect Molecular Biology (2011) February 20(1): 125-133. Epub 2010 Oct 14.



2010:


Distinct Olfactory Signaling Mechanisms in the Malaria Vector Mosquito Anopheles gambiae. 

Liu, C*. Pitts, R.J*., Bohbot, J., Jones, P.L., Wang, G. and Laurence J. Zwiebel

PLoS Biology (2010) August 31.

The Molecular Basis of Odor Coding in the Malaria Vector Mosquito Anopheles gambiae.

Wang,G., Carey, AF., Carlson, JR. and Laurence J. Zwiebel

Proceedings of the National Academy of Sciences USA (2010) March 2; 107(9): 4418-23. published ahead of print Feb. 16, 2010 doi:10.1073/pnas.0913392107.


Odour reception in the malaria mosquito Anopheles gambiae.

Carey, A. Wang, G., Su, CY., Zwiebel, LJ., and Carlson, J.R.

Nature (2010) Mar 4, 464 (7285): 66-71. EpubFebruary 3, doi: 10.1038/nature08834.



2009 and before:


Anopheles gambiae TRPA1 is a heat activated channel expressed in theromosenitive sensilla of female antennae.

Wang, G., Qiu, YT, Lu, T. Kwon, HW., Pitts, RJ and Zwiebel, LJ

European Journal of Neuroscience (2009) 30: 967-974.  


The molecular and cellular basis of olfactory-driven behavior in Anopheles gambiae larvae.

Xia Y*, Wang G*, Buscariollo D, Pitts RJ, Wenger H, Zwiebel LJ

Proceedings of the National Academy of Sciences USA (2008); 105(17):6433-8.


A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction.

Walker WB, Smith EM, Jan T, Zwiebel LJ

J Insect Physiol. (2008) Apr; 54(4):680-90.


Molecular Characterization of the Aedes aegypti Odorant Receptor Gene Family.

J. Bohbot*, R. J. Pitts*, H.W. Kwon, M. Rützler, H. M. Robertson and L. J. Zwiebel

Insect Molecular Biology (2007) Oct.; 16(5): 525-37. Epub 2007 Jul 17.

Odor Coding in the Maxillary Palp of the Malaria Vector Mosquito Anopheles gambiae. 

T. Lu*, G. Wang*, YT. Qiu,* J.Y. Young*, M. Rutzler, H.W. Kwon, R. J. Pitts, J. J.A. van Loon, J. R. Carlson, W. Takken, and L. J. Zwiebel

Current Biology (2007) Sept. 18; 17(18): 1533-1544. Epub 2007 Aug 30. 


G(alpha) encoding gene family of the malaria vector mosquito Anopheles gambiae: Expression analysis and immunolocalization of AG(alphaq) and AG(alphao) in female antennae.

Rutzler M, Lu T, Zwiebel LJ

Journal of Comparative Neurology. (2006) 499:533-545.


Olfactory responses in a gustatory organ of the malaria vector mosquito Anopheles gambiae.

Kwon HW, Lu T, Rutzler M, Zwiebel LJ

Proceedings of the National Academy of Sciences USA. (2006) 103:13526-13531.

Antennal Sensilla of Two Female Anopheles Sibling Species with Differing Host Ranges.

R. J. Pitts and L.J. Zwiebel

Malaria Journal (2006) 5:26


Identification and Characterization of an Odorant Receptor from the West Nile Virus Mosquito, Culex quinquefasciatus.

Yuanfeng Xia and Laurence J. Zwiebel

Insect Molecular Biology and Biochemistry, (2006) 36: 169-176.


Molecular Biology of Insect Olfaction: Recent Progress and Conceptual Models.

M. Rützler and L.J. Zwiebel

Journal of Comparative Physiology A. Neuroethology, Sensory, Neural and Behavioral Physiology (2005) 11: 1-14.


Odorant-Specific Requirements for Arrestin Function in Drosophila Olfaction.

C.E. Merrill, T. Sherertz, W.B. Walker, and L.J. Zwiebel

Journal of Neurobiology, (2005) Early View.


Identification of an Chemosensory Receptor from the Yellow Fever Mosquito, Aedes aegypti, that is Highly Conserved and Expressed in Olfactory and Gustatory Organs.

A.C. do Amoral Melo, M. Ruetzler, R. J. Pitts, and L.J. Zwiebel

Chemical Senses, (2004) 29:403-410.


Olfactory Regulation of Mosquito-Host Interactions.

L. J. Zwiebel and W. Takken

Insect Biochemistry and Molecular Biology (2004) 34/7:645-652.


A Highly Conserved Candidate Chemosensory Receptor Expressed in Both Olfactory and Gustatory Tissues in the Malaria Vector Mosquito, Anopheles gambiae.

R. J. Pitts, A. N. Fox and L.J. Zwiebel

Proceedings of the National Academy of Sciences USA, (2004) 101:5058-5063.


A Mosquito Odor Receptor for a Component of Human Sweat.

E. Hallem, A.N. Fox, L.J. Zwiebel, and J.R. Carlson

Nature, (2004) 427:212-213.


Molecular Characterization of Arrestin Family Members in the Malaria Vector Mosquito, Anopheles gambiae.

C.E. Merrill, R.J. Pitts, and L.J. Zwiebel

Insect Molecular Biology, (2003) 12 (6), 641-650.


Identification of a Distinct Family of Genes Encoding Atypical Odorant-Binding Proteins in the Malaria Vector Mosquito, Anopheles gambiae.

P.X. Xu, L.J. Zwiebel, and D. Smith

Insect Molecular Biology, (2003) 12 (6), 549-560.


G-protein Coupled Receptors in the Malaria Anopheles gambiae.

C.H. Hill, A.N. Fox, R.J. Pitts, L.H. Hunt, F.C. Collins, H.M. Robertson, and L.J. Zwiebel

Science, (2002) Oct4;298: 176-178.


A Cluster of Candidate Odorant Receptor from the Malaria Vector Mosquito, Anopheles gambiae.

A.N. Fox, R.J. Pitts, and L.J. Zwiebel

Chemical Senses, (2002) Jun;27 (5): 453-459.

Visual Arrestins in Olfactory Pathways of Drosophila and the Malaria Vector Mosquito Anopheles gambiae.

C.E. Merrill, R.J. Pitts, F.C. Kafatos, J.R. Carlson, and L.J. Zwiebel

Proceedings of the National Academy of Science USA (2002) 99:1633-1638.


Candidate Odorant Receptors from the Malaria Vector Mosquito Anopheles gambiae and Evidence of Downregulation in Response to Blood Feeding.

A.N. Fox, R.J. Pitts, H.M. Robertson, J.R. Carlson, and L.J. Zwiebel

Proceedings of the National Academy of Science USA, (2001) 98:14693-14697.


Isolation and Functional Characterization of the Xanthine Dehydrogenase gene of the Mediterranean fruit fly, Ceratitis capitata.

R.J. Pitts and L.J. Zwiebel

Genetics (2001) Aug; 158:1645-1655.


Genomic Organization and Characterization of the white locus from the Mediterranean fruitfly Ceratitis capitata.

L.M. Gomulski, R.J. Pitts, S. Costa, G. Saccone, C. Torti, A. Malacrida, F.C. Kafatos and L.J. Zwiebel

Genetics (2001) Mar;157(3):1245-55.