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Hight, Matthew
Interdisciplinary Materials Science

Research Information

Graduate Student, Interdisciplinary Materials Science

Research Area
My work involves the development of novel molecular imaging probes for the detection of cell death in vivo. A variety of scaffolds are used to develop libraries of small molecule, peptide, and protein based imaging agents. Prospective agents are screened using high-throughput biological assays. Finally, prospective probes are imaged in small animal xenografts of colorectal cancer using nuclear imaging techniques such as positron emission tomography (PET).

Ph.D. Thesis Advisor
Charles Manning, Imaging Sciences


Selected Publications

Microwave-assisted organic synthesis of a high-affinity pyrazolo-pyrimidinyl TSPO ligand. Tang, DW; Buck, JR; Hight, MR, Manning, HC, TETRAHEDRON LETTERS, 51, 4595-4598 , (2010)

Email: matthew.r.hight@Vanderbilt.Edu

Vanderbilt University