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McIntyre, James O
Research Professor of Cancer Biology
Research Professor of Radiology and Radiological Sciences

Research Information

Research interests include: in vivo molecular imaging of tumor-associated proteinases.


Selected Publications

A Novel In Vitro Assay to Assess Phosphorylation of 3 '-[F-18]fluoro-3 '-Deoxythymidine. Guo, N; Xie, JP; Manning, HC; Deane, NG; Ansari, MS; Coffey, RJ; Gore, J; Price, RR; Baldwin, RM; McIntyre, JO, MOLECULAR IMAGING AND BIOLOGY, 13, 257-264 , (2011)

IL-13 and T(H)2 cytokine exposure triggers matrix metalloproteinase 7-mediated Fas ligand cleavage from bronchial epithelial cells. Wadsworth, SJ; Atsuta, R; McIntyre, JO; Hackett, TL; Singhera, GK; Dorscheid, DR, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 126, 366-U73 , (2010)

Noninvasive in vivo imaging of MMP-7 activity. Soebbing, S; Tantawy, MN; Baldwin, RM; Peterson, TE; Matrisian, LM; McIntyre, JO, NUCLEAR MEDICINE AND BIOLOGY, 37, 708-708 , (2010)

Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents. Uddin, MJ; Crews, BC; Blobaum, AL; Kingsley, PJ; Gorden, DL; McIntyre, JO; Matrisian, LM; Subbaramaiah, K; Dannenberg, AJ; Piston, DW; Marnett, LJ, CANCER RESEARCH, 70, 3618-3627 , (2010)

Imaging proteolytic activity at primary and metastatic sites. Matrisian, LM; McIntyre, JO; Scherer, RL; Martin, MD, CLINICAL & EXPERIMENTAL METASTASIS, 26, 932-932 , (2009)

Mix and match nanodendrons for targeting and treatment of breast cancer metastases. Scherer, RL; Samuelson, LE; Lynch, CC; McIntyre, JO; Bornhop, DJ; Matrisian, LM, CLINICAL & EXPERIMENTAL METASTASIS, 26, 906-906 , (2009)

Monitoring of MMPs activity in vivo, non-invasively, using solubility switchable MRI contrast agent. Jastrzebska, B; Lebel, R; McIntyre, OJ; Paquette, B; Neugebauer, W; Escher, E; Lepage, M, PEPTIDES FOR YOUTH - THE PROCEEDINGS OF THE 20TH AMERICAN PEPTIDE SYMPOSIUM, 611, 453-454 , (2009)

PHOSPHORYLATION AND UPTAKE OF 3-DEOXY-3-[18F]FLUOROTHYMIDINE IN COLON CANCER CELL LYSATES. Guo, N; Xie, J; Manning, HC; Deane, NG; Ansari, MS; Coffey, RJ; Gore, J; Price, RR; Baldwin, RM; McIntyre, JO, JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 52, S414-S414 , (2009)

Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth. Martin, MD; Fingleton, B; Lynch, CC; Wells, S; McIntyre, JO; Piston, DW; Matrisian, LM, CLINICAL & EXPERIMENTAL METASTASIS, 25, 877-885 , (2008)

Functional colonography of Min mice using dark lumen dynamic contrast-enhanced MRI. Quarles, CC; Lepage, M; Gorden, DL; Fingleton, B; Yankeelov, TE; Price, RR; Matrisian, LM; Gore, JC; McIntyre, JO, MAGNETIC RESONANCE IN MEDICINE, 60, 718-726 , (2008)

Imaging matrix metalloproteinases in cancer. Scherer, RL; McIntyre, JO; Matrisian, LM, CANCER AND METASTASIS REVIEWS, 27, 679-690 , (2008)

Optical Imaging of Matrix Metalloproteinase-7 Activity In Vivo Using a Proteolytic Nanobeacon. Scherer, RL; VanSaun, MN; McIntyre, JO; Matrisian, LM, MOLECULAR IMAGING, 7, 118-131 , (2008)

Monitoring of MMPs activity in vivo, non-invasively, using solubility switchable MRI contrast agent. Jastrzebska, E; Label, R; McIntyre, JO; Paquette, B; Escher, E; Lepage, M, BIOPOLYMERS, 88, 601-601 , (2007)

Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch. Lepage, M; Dow, WC; Melchior, M; You, Y; Fingleton, B; Quarles, CC; Pepin, C; Gore, JC; Matrisian, LM; McIntyre, JO, MOLECULAR IMAGING, 6, 393-403 , (2007)

Salivary proteinase activity: A potential biomarker for preterm premature rupture of the membranes. Menon, R; McIntyre, JO; Matrisian, LM; Fortunato, SJ, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 194, 1609-1615 , (2006)

Fish oil diet increases polyunsaturated fatty acids (PUFA) in colonic phospholipids detected by computational lipidomics and reduces growth of colonic polyps in the Min mouse.. McIntyre, JO; Byrne, M; Zheng, XJ; Carter, KJ; Ivanova, PT; Milne, SB; Forrester, JS; Everest, S; Matrisian, LM; Brown, HA, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 14, 2754S-2754S , (2005)

Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells. Harrell, PC; McCawley, LJ; Fingleton, B; McIntyre, JO; Matrisian, LM, EXPERIMENTAL CELL RESEARCH, 303, 308-320 , (2005)

Proteinase activity in human and murine saliva as a biomarker for proteinase inhibitor efficacy. Fingleton, B; Menon, R; Carter, KJ; Overstreet, PD; Hachey, DL; Matrisian, LM; McIntyre, JO, CLINICAL CANCER RESEARCH, 10, 7865-7874 , (2004)

Molecular imaging of proteolytic activity in cancer. McIntyre, JO; Matrisian, LM, JOURNAL OF CELLULAR BIOCHEMISTRY, 90, 1087-1097 , (2003)


Phone: 615-936-2913
Email: oliver.mcintyre@vanderbilt.edu
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