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14th Annual Nanoscience and Nanotechnology Forum

14th Annual Nanoscience and Nanotechnology Forum
Wednesday, November 13
Nanoday will be held in Buttrick Hall from 1:00-2:30, and in Featheringill Hall for remainder of event.

Schedule of Events 

1:10 - 1:25  Welcome Sandra Rosenthal, Chemistry

1:25 - 1:45   Science Outreach: Importance, Programs, and Opportunities 
Gabriel LeBlanc, Graduate Student, Chemistry 

1:45 - 2:05     Nanotechnology for an Implantable Artificial Kidney 
                        William Fissell, Nephrology

2:05 - 2:25     Plasmon Enhanced Generation III Solar Cells 
Rizia Bardhan, Chemical and Biomolecular Engineering

2:25 - 3:10     POSTER SESSION

3:10 - 3:30 Microfluidic Materials from Cotton Candy  
Leon Bellan, Mechanical Engineering

3:30 - 3:50     Plasmon-Exciton Hybrids in One and Two Dimensions  
Richard Haglund, Physics 

3:50 - 4:10    hAuNP Imaging of mRNA in Live Cells 
David Wright, Chemistry

4:10 - 4:50     POSTER SESSION

4:50 - 6:00     KEYNOTE SPEAKER  
                        Applying Physico-Chemical Laws in Oncology: Predicting Combinatorial Targeted
Therapies for Glioblastoma Cancer Patients  
James Heath, Elizabeth W. Gilloon Professor of Chemistry, Caltech
                        Professor of Molecular and Medical Pharmacology, UCLA
Director, NanoSystems Biology Cancer Center


Heath Abstract. The dream of personalized medicine is effectively the goal of customizing healthcare for the individual patient.  Certain diseases, including many advanced stage cancers, exhibit such patient-to-patient variability that a true personalized medicine approach may be the only route to effective treatment.  A prototypical disease example is the brain cancer glioblastoma multiforme (GBM).  At the molecular level, it is rare for any two GBM patients to appear as if they have the same disease.   Diseases such as GBM are not only heterogeneous across patient populations, but each tumor can also be highly heterogeneous at the cellular level – a trait that apparently contributes to the ability of such tumors to resist treatments.  From a traditional biology perspective, this heterogeneity causes GBM to be viewed as a complex (or ‘hard to understand’) disease.  However, a GBM tumor, as viewed by a physicist, might appear as a stable ‘organ’, with a stability that emerges exactly because of the heterogeneity of the cellular components.  Consider, as an analogy, the robust nature of a diverse economy.  That physical perspective implies that quantitatively capturing the cellular heterogeneity within the tumor can provide a route towards constructing the robust state of the tumor.  That picture, in turn, can provide insight into how to disrupt that robust state by targeting the signaling networks essential for tumor maintenance, as well as anticipating mechanisms of resistance.  I will discuss technology platforms and approaches we have developed for just this purpose, and how those platforms are beginning to be applied within the clinic for patient benefit.

Heath Bio. Jim Heath is the Elizabeth Gilloon Professor and Professor of Chemistry at Caltech, and Professor of Molecular and Medical Pharmacology at UCLA.  He directs the National Cancer Institute funded NSB Cancer Center. He received his Ph.D. in 1988 from Rice University where he was the principle graduate student involved in the discovery of C60 and the fullerenes.  He was a Miller Fellow at UC Berkeley before joining the research staff at IBM Watson Labs in 1991.  He took a faculty position at UCLA in 1994, and moved to Caltech in 2003.  He has received a number of awards, including the Irving Weinstein Award from the American Association of Cancer Researchers and the Sackler prize in the physical sciences.  In 2009 he was named by Forbes as one of the top 7 innovators in the world.
Disclosures:  Founder and Board Member: Integrated Diagnostics, Momentum Biosciences. Co-Founder: NanoSys. Board Member: Sofie Biosciences. 

2013 Poster Submissions

1. In vivo imaging of gold nanorod pharmacokinetics using photothermal optical coherence tomography
  Jason Tucker-Schwartz, Biomedical Engineering (Skala)

2. Integration of Photosystem I with Semi-Conducting and Carbon-Based Materials for Solar Energy
Gabriel LeBlanc, Chemistry (Cliffel)

3.  Optoelectronic Nanoprobes for the Neural Network
Kristina Kitko, Interdisciplinary Materials Science (Zhang & Xu)

4. Tunable Properties of Shape Memory Polymers for Minimally Invasive Vascular Constructs
Tim Boire, Biomedical Engineering (Sung) 

5. Zero Index Metamaterial for Directive Emission
Yuanmu Yang, Interdisciplinary Materials Science (Valentine & Weiss)

6. Electrochemical Preparation of Polyaniline-Photosystem I Composite Films for Biohybrids Solar Energy
Evan Gizzie, Chemistry (Cliffel)

7. In Situ Peptide Nucleic Acid Synthesis from Porous Silicon as a Functionalized Strategy for Drug Delivery
and Biosensing
Kelsey Beavers, Interdisciplinary Materials Science (Duvall & Weiss)

8. Size- and Shape-controlled Synthesis of Wurtzite CuInS2 Nanoparticles for Photocatalytic Water
Bryson Howard, Chemistry (Macdonald)

9.  Local Delivery of Lipid-Conjugated siRNA from Poly(ester urethane) Scaffolds
Samantha Sarett, Biomedical Engineering (Duvall)

10. Active Modulation of Plasmon-Induced Transparency in Gold: VO2 Hybrid
Christina McGahan, Physics (Haglund)

11. Hairpin DNA Functionalized Gold Nanoparticles for Live Cell Imaging of mRNA
Alexis Wong, Chemistry (Wright)

12. Plasmon-Enhanced Photoluminescence in Ag-Decorated ZnO/MgO Core-Shell Nanowires
Claire Marvinney & Daniel Mayo, Interdisciplinary Materials Science (Haglund) 

13. Complete Water Splitting with Hybrid Nanoparticles and Hole-Extracting Ligands
Andrew La Croix, Chemistry (Macdonald)

14, Polymer Nano-needle Templates User-defined Features for Control of Stem Cell Function
Spencer Crowder, Biomedical Engineering (Sung) 

15. Ultrafast Dynamics of Graded Alloy CdSXSe1-X Semiconductor Nanocrystals 
Joe Keene, Chemistry (Rosenthal)

15.  Polymer nano-needle templates user-defined features for control of stem cell function
Spencer Crowder, Biomedical Engineering (Sung)

16.  Probing and Controlling Photothermal Heat Generation in Plasmonic Nanostructures
Wei Li, Mechanical Engineering (Valentine) 

17. Crystal-Bound vs. Surface-Bound Thiols on Nanoparticles
Michael Turo, Chemistry (Macdonald) 

18. Efficient Forward Second Harmonic Generation from Archimedean Nanospirals
Roderick Davidson, Physics (Haglund) 

19. Coffee Rings as Low-Resource Diagnostics: Detection of Malaria Biomarker Plasmodium falciparum
Histidine-Rich Protein-2 Using a Surface-Coupled Ring of Ni(II)NTA Gold Particles
  Christopher Gulka, Chemistry (Wright)

20. Two-step Immune- and Proximity-activated Targeting for Delivery of MMP-13 siRNA to Inhibit Osteoarthritis
Thomas Werfel, Biomedical Engineering (Duvall) 

21. Photoluminescence Enhancement and Raman Response in Single-Layer MoS2 Exposed to X-Rays
and Ozone Plasma 
Roel Flores, Interdisciplinary Materials Science (Xu)

22. Optimizing PEG Length for Enhanced In Vivo Pharmacokinetics of a Micellar siRNA Carrier
Martina Miteva, Biomedical Engineering (Duvall & Giorgio)

23. Delivery of Diblock Copolymer/Plasmid DNA Polyplexes From Polyurethane Scaffolds
Elizabeth Adolph, Chemical and Biomolecular Engineering (Guelcher)

24. Hermadynamic Targeted Theranostic Nanoparticles for Prophylatic Treatment of Cardiovascular Disease
Lucas Hofmeister, Biomedical Engineering (Sung) 

25. Progress Towards the Synthesis of Au@SiO2-Cu2-XSe Hybrid Nanoparticles for Surface Plasmon Studies
Summer Arrowood, Chemistry (Macdonald)

26. Nanopore Formation Investigation in Silicon Nitride/ Silicon/ Silicon Nitride Stacks
Chengzhu Qi, Electrical Engineering (Fauchet)

27. Needle in the Hay: Correlating the Atomic Structure of a Single Core/ Shell Semiconductor Nanocrystal with
Its Photophysical Properties
Noah Orfield, Chemistry (Rosenthal)

 28.  MK2 Inhibitory Peptide Delivery with Endosomolytic Nano-Polyplexes Prevents Vasoconstriction and Intimal
Hyperplasia in Human Saphenous Vein Bypass Grafts
Kameron Kilchrist, Biomedical Engineering (Duvall)

29. Nanostructured MoS2 Electrodes for Polysulfide Reduction
Shane Finn, Chemistry (Macdonald) 

 1st year student posters submissions 

1.  All Electron Force Calculation For Defected Silicon
Bradly Baer, Interdisciplinary Materials Science (Walker)

2. Probing Structural Phase Transitions in Strongly Correlated Material
Alice Leach, Interdisciplinary Materials Science (Haglund)

3. Molecular Dynamics Simulations of Radiation Damage in YAG for Photoluminescence
Matthew Gerboth, Interdisciplinary Materials Science (Walker) 

James R. Heath
Vanderbilt University