Articles Published in Peer-Reviewed Journals

Fenn,LS and McLean,JA. Structural Resolution of Carbohydrate Positional and Structural Isomers Based on Gas-Phase Ion Mobility-Mass Spectrometry, Phys. Chem. Chem. Phys., 13, 2196-2205, 2011

Velkovsky,M, Snider,R, Cliffel,DE, Wikswo,JP. Modeling the Measurements of Cellular Fluxes in Microbioreactor Devices Using Thin Enzyme Electrodes, Journal of Mathematical Chemistry, 49, 251-275, 2011

LeDuc,PR, Messner,WC, Wikswo,JP. How Do Control-Based Approaches Enter into Biology?, Annu. Rev. Biomed. Engr., 13, 369-396, 2011  DOI Link

Yang,R, Lenaghan,SC, Wikswo,JP, Zhang,M. External Control of the GAL Network in S. Cerevisiae: A View From Control Theory, PloS. One., 6, e19353, 2011  DOI Link

Dukes III,AD, Samson,PC, Keene,JD, Davis,LM, Wikswo,JP, Rosenthal,SJ. Single-Nanocrystal Spectroscopy of White-Light-Emitting CdSe Nanocrystals, The Journal of Physical Chemistry A, 115, 4076-4081, 2011  DOI Link

Gao,Y, Majumdar,D, Jovanovic,B, Shaifer,C, Lin,P, Zijlstra,A, Webb,D, Li,D. A Versatile Valve-Enabled Microfluidic Cell Co-Culture Platform and Demonstration of Its Applications to Neurobiology and Cancer Biology, Biomed. Microdevices, 13, 539-548, 2011  DOI Link

Sidorov,VY, Uzelac,I, Wikswo,JP. Regional Increase of Extracellular Potassium Leads to Electrical Instability and Reentry Occurrence Through the Spatial Heterogeneity of APD Restitution, Am. J. Physiol. Heart, 301, H209-H220, 2011  DOI Link

Liu,Y, Markov,D, Wikswo,J, McCawley,L. Microfabricated Scaffold-Guided Endothelial Morphogenesis in Three-Dimensional Culture, Biomed. Microdevices, 13, 837-846, 2011  DOI Link

Schmidt,MD, Vallabhajosyula,RR, Jenkins,JW, Hood,JE, Soni,AS, Wikswo,JP, Lipson,H. Auotmated Refinement and Inference of Analytical Models for Metabolic Networks, Phys. Biol., 8, 055011 2011  DOI Link

Kerr,TJ, Gant-Branum,RL, McLean,JA. Multiplexed Analysis of Peptide Functionality Using Lanthanide-Based Structural Shift Reagents, Int. J. Mass Spectrom., 307, 28-32, 2011  DOI Link

Lubbers,B and Baudenbacher,F. Isothermal Titration Calorimetry in Nanoliter Droplets With Subsecond Time Constants, Anal. Chem., 80, 7955-7961, 2011  DOI Link

Addae-Mensah,KA, Retterer,S, Opalenik,S, Thomas,D, Lavrik,NV, Wikswo,JP. Cryogenic Etching of Silicon: an Alternative Method for Fabrication of Vertical Microcantilever Master Molds, J. Microelectromech. S., 19, 64-74, 2010

Ayati,BP, Edwards,CM, Webb,GF, Wikswo,JP. A Mathematical Model of Bone Remodeling Dynamics for Normal Bone Cell Populations and Myeloma Bone Disease, Biology Direct, 5, 28 2010

Darby,S, Moore,M, Wikswo,JP, Reiserer,R, Friedlander,T, Schaffer,DK, Seale,KT. A Metering Rotary Nanopump for Microfluidic Systems, Lab Chip, 10, 3218-3226, 2010

Enders,JR, Marasco,CC, Kole,A, Nguyen,B, Sundarapandian,S, Seale,KT, Wikswo,JP, Mclean,JA. Towards Monitoring Real-Time Cellular Response Using an Integrated Microfluidics-MALDI/NESI-Ion Mobility-Mass Spectrometry Platform, IET Syst. Biol., 4, 416-427, 2010

Gant-Branum,RL, Broussard,JA, Mahsut,A, Webb,DJ, Mclean,JA. Identification of Phosphorylation Sites Within the Signaling Adaptor APPL1 by Mass Spectrometry, J. Proteome. Res., 9, 1541-1548, 2010

Ges,IA and Baudenbacher,F. Enzyme Electrodes to Monitor Glucose Consumption of Single Cardiac Myocytes in Sub-Nanoliter Volumes, Biosens. Bioelectron., 25, 1019-1024, 2010

Harkness,KM, Fenn,LS, Cliffel,DE, McLean,JA. Surface Fragmentation of Complexes From Thiolate Protected Gold Nanoparticles by Ion Mobility-Mass Spectrometry, Anal. Chem., 82, 3061-3066, 2010

Harkness,KM, Hixson,BC, Fenn,LS, Turner,BN, Rape,AC, Simpson,CA, Huffman,BJ, Okoli,TC, McLean,JA, Cliffel,DE. A Structural Mass Spectrometry Strategy for the Relative Quantitation of Ligands on Mixed Monolayer-Protected Gold Nanoparticles, Anal. Chem., 82, 9268-9274, 2010

Harkness,KM, Cliffel,DE, McLean,JA. Characterization of Thiolate-Protected Gold Nanoparticles by Mass Spectrometry, The Analyst, 135, 868-874, 2010

Jowhar,D, Wright,G, Samson,PC, Wikswo,JP, Janetopoulos,C. Open Access Microfluidic Device for the Study of Cell Migration Diring Chemotaxis, Integrative Biology, 2, 648-658, 2010

Kerr,TJ and McLean,JA. Peptide Quantitation Using Primary Amine Selective Metal Chelation Labels for Mass Spectrometry, Chem. Commun., 46, 5479-5481, 2010

Kliman,M, Vijayakrishnan,N, Wang,L, Tapp,JT, Broadie,K, McLean,JA. Structural Mass Spectrometry Analysis of Lipid Changes in a Drosophila Epilepsy Model Brain, Mol. Biosyst., 6, 958-966, 2010

Markov,DA, Samson,PC, Schaffer,DK, Dhummakup,A, Wikswo,JP, Shor,LM. Window on a Microworld: Simple Microfluidic Systems for Studying Microbial Transport in Porous Media, JoVE, 39, 2010  DOI Link

Markov,DA, Manuel,S, Shor,L, Opalenik,SR, Wikswo,JP, Samson,PC. Tape Underlayment Rotary-Node (TURN) Valves for Simple on-Chip Microfluidic Flow Control, Biomed. Microdevices, 12, 135-144, 2010

McBride,KK, Roth,BJ, Sidorov,VY, Wikswo,JP, Baudenbacher,FJ. Measurements of Transmembrane Potential and Magnetic Field at the Apex of the Heart, Biophys. J., 99, 3113-3118, 2010

McLean,JR, Mclean,JA, Wu,ZX, Becker,C, Perez,LM, Pace,CN, Scholtz,JM, Russell,DH. Factors That Influence Helical Preferences for Singly Charged Gas-Phase Peptide Ions: The Effects of Multiple Potential Charge-Carrying Sites, J. Phys. Chem. B, 114, 809-816, 2010

Rachakonda,G, Sekhar,K, Jowhar,D, Samson,PC, Wikswo,JP, Beauchamp,RD, Sasi,S, Datta,PK, Freeman,ML. Increased Cell Migration and Plasticity in Nrf2 Deficient Cancer Cell Lines, Oncogene, 29, 3703-3714, 2010  DOI Link

Ridenour,WB, Kliman,M, McLean,JA, Caprioli,RM. Structural Characterization of Phospholipids and Peptides Directly From Tissue Sections by MALDI Traveling-Wave Ion Mobility-Mass Spectrometry, Anal. Chem., 82, 1881-1889, 2010

Seale,KT, Faley,SL, Chamberlain,J, Wikswo,JP, Jr. Macro to Nano: A Simple Method for Transporting Cultured Cells From Milliliter Scale to Nanoliter Scale, Exp. Biol. Med., 235, 777-783, 2010

Snider,RM, McKenzie,JR, Kraft,L, Kozlov,E, Wikswo,JP, Cliffel,DE. The Effects of Cholera Toxin on Cellular Energy Metabolism, Toxins, 2, 632-648, 2010

Sundarapandian,S, May,JC, McLean,JA. Dual Source Ion Mobility-Mass Spectrometer for Direct Comparison of Electrospray Ionization and MALDI Collision Cross Section Measurements, Anal. Chem., 82, 3247-3254, 2010

Fenn,LS, Kliman,M, Mahsut,A, Zhao,SR, Mclean,JA. Characterizing Ion Mobility-Mass Spectrometry Conformation Space for the Analysis of Complex Biological Samples, Analytical and Bioanalytical Chemistry, 394, 235-244, 2009   DOI Link

Irimia,A, Swinney,KR, Wikswo,JP. Partial Independence of Bioelectric and Biomagnetic Fields and Its Implications for Encephalography and Cardiography, Phys. Rev. E, 79, 051908, 2009  DOI Link

Eklund,SE, Thompson,RG, Snider,RM, Carney,CK, Wright,DW, Wikswo,J, Cliffel,DE. Metabolic Discrimination of Select List Agents by Monitoring Cellular Responses in a Multianalyte Microphysiometer, Sensors, 9, 2117-2133, 2009   DOI Link

Ma,X, Lynch,H, Scully,PC, Hutson,MS. Probing Embryonic Tissue Mechanics With Laser Hole Drilling. Physical Biology, 6, 036004, 2009  DOI Link

An,SS, Kim,J, Ahn,K, Trepat,X, Drake,KJ, Kumar,S, Ling,G, Purington,C, Rangasamy,T, Kensler,TW et al. Cell Stiffness, Contractile Stress and the Role of the Extracellular Matrix, Biochem. Biophys. Res. Commun., 382, 697-703, 2009  DOI Link

Botzolakis,EJ, Maheshwari,A, Feng,HJ, Lagrange,AH, Shaver,JH, Kassebaum,NJ, Venkataraman,R, Baudenbacher,F, MacDonald,RL. Achieving Synaptically Relevant Pulses of Neurotransmitter Using PDMS Microfluidics, J. Neurosci. Methods, 177, 294-302, 2009   DOI Link

Elzie,CA, Colby,J, Sammons,MA, Janetopoulos,C. Dynamic Localization of G Proteins in Dictyostelium Discoideum, J. Cell Sci., 122, 2597-2603, 2009  DOI Link

Faley,SL, Copland,M, Wlodkowic,D, Kolch,W, Seale,KT, Wikswo,JP, Cooper,JM. Microfluidic Single Cell Arrays to Interrogate Signalling Dynamics of Individual, Patient-Derived Hematopoietic Stem Cells, Lab Chip, 9, 2659-2664, 2009  DOI Link

Gray,RA, Wikswo,JP, Otani,NF. Origin Choice and Petal Loss in the Flower Garden of Spiral Wave Tip Trajectories, Chaos, 19, 033118 2009   DOI Link

Mclean,JA. The Mass-Mobility Correlation Redux: the Conformational Landscape of Anhydrous Biomolecules, J. Am. Soc. Mass. Spect., 20, 1775-1781, 2009  DOI Link

Easley,CJ, Benninger,RKP, Shaver,JH, Steven Head,W, Piston,DW. Rapid and Inexpensive Fabrication of Polymeric Microfluidic Devices Via Toner Transfer Masking, Lab Chip, 9, 1119-1127, 2009

Enders,JR and Mclean,JA. Chiral and Structural Analysis of Biomolecules Using Mass Spectrometry and Ion Mobility-Mass Spectrometry, Chirality, 21, E253-E264, 2009

Fenn,LS and Mclean,JA. Simultaneous Glycoproteomics on the Basis of Structure Using Ion Mobility-Mass Spectrometry, Mol. Biosyst., I5, 1298-1302, 2009

Holcomb,MR, Woods,MC, Uzelac,I, Wikswo,JP, Gilligan,JM, Sidorov,VY. The Potential of Dual Camera System for Multimodal Imaging of Cardiac Electrophysiology and Metabolism, Exp. Biol. Med., 234, 1355-1373, 2009

Wlodkowic,D, Faley,S, Zagnoni,M, Wikswo,JP, Cooper,JM. Microfluidic Single-Cell Array Cytometry for the Analysis of Tumour Apoptosis, Anal. Chem., 81, 5517-5523, 2009

Hutson,MS, Veldhuis,J, Ma,X, Lynch,HE, Cranston,PG, Brodland,GW. Combining Laser Microsurgery and Finite Element Modeling to Assess Cell-Level Epithelial Mechanics, Biophys. J., 97, 3075-3085, 2009  DOI Link

Wang,W, Shor,LM, LeBoeuf,EJ, Wikswo,JP, Taghon,GL, Kosson,DS. Protozoan Migration in Bent Microfluidic Channels, Appl. Environ. Microbiol., 74, 1945-1949, 2008   DOI Link

Gorman,BR and Wikswo,JP, Characterization of Transport in Microfluidic Gradient Generator, Microfluidics and Nanofluidics, 4, 273-285, 2008   DOI Link

Abbas,RA, Lin,S-F, Mashburn,D, Xu,J, Wikswo,JP, A Phased-Array Stimulator System for Studying Planar and Curved Cardiac Activation Wave Fronts, IEEE Trans. Biomed. Eng., 55: 222-229, 2008  DOI Link

Georgescu W, Jourquin J, Estrada L, Anderson ARA, Quaranta V, Wikswo JP, Model-Controlled Hydrodynamic Focusing to Generate Multiple Overlapping Gradients of Surface-Immobilized Proteins in Microfluidic Devices, Lab on a Chip, 8: 238-244, 2008  DOI Link

Evertson,DW, Holcomb,MR, Eames,M, Bray,M, Sidorov,VY, Xu,J, Wingard,H, Dobrovolny,HM, Woods,MC, Gauthier,DJ et al. High-Resolution High-Speed Panoramic Cardiac Imaging System, IEEE Trans. Biomed. Eng., 55, 1241-1243, 2008   DOI Link

Snider,RM, Ciobanu,M, Rue,AE, Cliffel,DE, A Multiwalled Carbon Nanotube/Dihydropyran Composite Film Electrode for Insulin Detection in a Microphysiometer Chamber, Anal.Chim.Acta, 609: 44-52, 2008  DOI Link

Ges,IA, Dzhura,IA, Baudenbacher,FJ. On-Chip Acidification Rate Measurements From Single Cardiac Cells Confined in Sub-Nanoliter Volumes, Biomed. Microdevices, 10, 347-354, 2008  DOI Link

Xu,J, Reiserer,R, Tellinghuisen,J, Wikswo,JP, Baudenbacher,FJ. A Microfabricated Nanocalorimeter: Design, Characterization, and Chemical Calibration, Anal. Chem., 80, 2728-2733, 2008   DOI Link

Jayagopal,A, Sussman,EM, Shastri,VP. Functionalized Solid Lipid Nanoparticles for Trans-Endothelial Delivery, IEEE Trans. NanoBiosci., 7, 28-34, 2008   DOI Link

Diniz Oliveira,HF, Weiner,AA, Majumdar,A, Shastri,VP. Non-Covalent Surface Engineering of an Alloplastic Polymeric Bone Graft Material for Controlled Protein Release, Journal of Controlled Release, 126, 237-245, 2008   DOI Link

Gruver,JS, Wikswo,JP, Chung,CY. 3'-Phosphoinositides Regulate the Coordination of Speed and Accuracy During Chemotaxis, Biophys. J., 95, 4057-4067, 2008   DOI Link

Liu,Y, Sai,JG, Richmond,A, Wikswo,JP. Microfluidic Switching System for Analyzing Chemotaxis Responses of Wortmannin-Inhibited HL-60 Cells, Biomed. Microdevices, 10, 499-507, 2008  DOI Link

Harris,MP, Kim,E, Weidow,B, Wikswo,JP, Quaranta,V. Migration of Isogenic Cell Lines Quantified by Dynamic Multivariate Analysis of Single-Cell Motility, Cell Adhesion & Migration, 2, 127-136, 2008

Sai,J, Raman,D, Liu,Y, Wikswo,J, Richmond,A. Parallel Phosphatidylinositol 3-Kinase (PI3K)-Dependent and Src-Dependent Pathways Lead to CXCL8-Mediated Rac2 Activation and Chemotaxis, J. Biol. Chem., 283, 26538-26547, 2008  DOI Link

Ges,IA and Baudenbacher,F. Microfluidic Device to Confine Single Cardiac Myocytes in Sub-Nanoliter Volumes for Extracellular PH Measurements, J. Exp. Nanosci., 3, 63-75, 2008 DOI Link

Ciobanu,M, Taylor,DE, Wilburn,JP, Cliffel,DE. Glucose and Lactate Biosensors for Scanning Electrochemical Microscopy Imaging of Single Live Cells, Anal. Chem., 80, 2717-2727, 2008   DOI Link

Irimia,A and Wikswo,JP, Jr. Gastrointestinal Arrhythmias Are Associated With Statistically Significant Fluctuations in Systemic Information Dimension, Physiol. Meas., 29, N33-N40, 2008   DOI Link

Faley,S, Seale,K, Hughey,J, Schaffer,DK, VanCompernolle,S, McKinney,B, Baudenbacher,F, Unutmaz,D, Wikswo,JP. Microfluidic Platform for Real-Time Signaling Analysis of Multiple Single T Cells in Parallel, Lab Chip, 8, 1700-1712, 2008   DOI Link

Sidorov,VY, Holcomb,MR, Woods,MC, Gray,RA, Wikswo,JP. Effects of Unipolar Stimulation on Voltage and Calcium Distributions in the Isolated Rabbit Heart, Basic Research in Cardiology, 103, 537-551, 2008  DOI Link

Seale,KT, Reiserer,RS, Markov,DA, Ges,IA, Wright,C, Janetopoulos,C, Wikswo,JP. Mirrored Pyramidal Wells for Simultaneous Mutiple Vantage Point Microscopy, J. Microsc., 232, Pt.1, 1-6, 2008   DOI Link

Holcomb,MR, Bekele,RY, Lima,EA, Wikswo,JP. USB-Powered and -Controlled Isolated Constant-Current Physiological Stimulator, Rev. Sci. Instrum., 79, 126103 2008  DOI Link

Maleckar,MM, Woods,MC, Sidorov,VY, Holcomb,MR, Mashburn,DN, Wikswo,JP, Trayanova,NA. Polarity Reversal Lowers Activation Time During Diastolic Field Stimulation of the Rabbit Ventricles: Insights into Mechanisms, Am. J. Physiol. Heart, 295, H1626-H1633, 2008   DOI Link

Benninger,RKP, Zhang,M, Head,WS, Satin,LS, Piston,DW. Gap Junction Coupling and Calcium Waves in the Pancreatic Islet, Biophys. J., 95, 5048-5061, 2008   DOI Link

Hutson,MS, Brodland,GW, Yang,J, Viens,D. Cell Sorting in Three Dimensions: Topology, Fluctuations, and Fluidlike Instabilities, Phys. Rev. Lett., 101, 148105 2008   DOI Link

Hutson,MS. Physical Aspects of Developmental Biology: 21st Century Perspectives 'On Growth and Form' - Preface, Physical Biology, 5, E01 2008   DOI Link

Hutson,MS and Ma,XY. Mechanical Aspects of Developmental Biology: Perspectives On Growth and Form in the (Post)-Genomic Age, Physical Biology, 5, 015001 2008   DOI Link

Xiao,Y, Guo,M, Zhang,P, Shanmugam,G, Polavarapu,PL, Hutson,MS. Wavelength-Dependent Conformational Changes in Collagen After Mid-Infrared Laser Ablation of Cornea, Biophys. J., 94, 1359-1366, 2008   DOI Link

Werdich,AA, Lima,EA, Dzhura,I, Singh,MV, Li,J, Anderson,ME, Baudenbacher,FJ. Differential Effects of Phospholamban and Ca²⁺/Calmodulin-Dependent Kinase II on [Ca²⁺]_i Transients in Cardiac Myocytes at Physiological Stimulation Frequencies, Am. J. Physiol. Heart, 294, 2352-2362, 2008   DOI Link

Baudenbacher,F, Schober,T, Pinto,JR, Sidorov,VY, Hilliard,F, Solaro,RJ, Potter,JD, Knollmann,BC. Myofilament Ca2+ Sensitization Causes Susceptibility to Cardiac Arrhythmia in Mice, J. Clin. Invest., 118, 3893-3903, 2008  DOI Link

Weiss,BP, Fong,LE, Vali,H, Lima,EA, Baudenbacher,FJ. Paleointensity of the Ancient Martian Magnetic Field, Geophys. Res. Lett., 35, L23207 2008  DOI Link

Addae-Mensah,KA, Kassebaum,NJ, Bowers,MJ, II, Reiserer,RS, Rosenthal,SJ, Moore,PE, Wikswo,JP, A Flexible, Quantum Dot-Labeled Cantilever Post Array for Studying Cellular Microforces, Sensors and Actuators A-Physical, 136: 385-397, 2007  DOI Link

Addae-Mensah,KA, Reiserer,RS, Wikswo,JP, Poly(Vinyl Alcohol) As a Structure Release Layer for Microfabrication of Polymer Composite Structures, J Micromech Microeng, 17: N41-N46, 2007  DOI Link

Bornhop,DJ, Latham,JC, Kussrow,A, Markov,DA, Jones,RD, Sorensen,HS , Free-Solution, Label-Free Molecular Interactions Studied by Back-Scattering Interferometry, Science, 317: 1732-1736, 2007  DOI Link

Ges,IA, Ivanov,BL, Werdich,AA, Baudenbacher,FJ, Differential pH Measurements of Metabolic Cellular Activity in Nl Culture Volumes Using Microfabricated Iridium Oxide Electrodes, Biosens Bioelectronics, 22: 1303-1310, 2007  DOI Link

Lipski,AM, Jacquiery,C, Choi,H, Eberli,D, Stevens,MM, Martin,I, Chen,I-W, Shastri,VP, Nanoscale engineering of biomaterial surfaces, Advanced Materials, 19(4): 553-557, 2007  DOI Link

Hutson, MS and Ma, X , Plasma and Cavitation Dynamics during Pulsed Laser Microsurgery In Vivo, Phys Rev Lett, 99, 158104, 2007  DOI Link

Mishra,A, Lu,Y, Choe,AS, Aldroubi,A, Gore,JC, Anderson,AW, Ding,Z, An Image-Processing Toolset for Diffusion Tensor Tractography, Magn Reson Imaging, 25: 365-376, 2007  DOI Link

Sussman,E, Clarke,MB, Shastri,VP, A Single Step Process to Produce Surface-Functionalized Nanoparticles from Non-Functionalized Degradable Polymers, Langmuir, 23(24): 12275-12279, 2007  DOI Link

Vajandar,SK, Xu,D, Markov,D, Wikswo,JP, Hofmeister,W, Li,D, SiO₂-Coated Porous Anodic Alumina Membrane for Electroosmotic Pumping, Nanotechnology, 18, 275705, 2007  DOI Link

Weiner,AA, Shuck,D, Bush,J, Shastri,VP, Optimization of photocrosslinked anhydride systems for bone augmentation applications: characterization of in vitro degradation, Biomaterials, 28: 5259-5270, 2007  DOI Link

Xu,X, Shastri,VP, A Modular Approach to the Synthesis of Property-Tunable Biodegradable Polyesters Derived from Poly(e-Caprolactone), Corrosion Engineering Science and Technology, 42(4): 293-299 (Invited Paper), 2007  DOI Link

Mashburn DN, Hinkson SJ, Woods MC, Gilligan JM, Holcomb MR, Wikswo JP, A High-Voltage Cardiac Stimulator for Field Shocks of a Whole Heart in a Bath, Review of Scientific Instruments, 78, 104302, 2007  DOI Link

Sidorov VY, Woods MC, Baudenbacher F., Cathodal Stimulation in the Recovery Phase of a Propagating Planar Wave in the Rabbit Heart Reveals Four Stimulation Mechanisms., J Physiol, 583(Pt 1):237-250, 2007  DOI Link

Werdich AA, Baudenbacher F, Dzhura I, Jeyakumar LH, Kannankeril PJ, Fleischer S, LeGrone A, Milatovic D, Aschner M, Strauss AW, Anderson ME, Exil VJ., Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice, Am J Physiol Heart Circ Physiol, 292(5):H2202-H2211, 2007  DOI Link

Edwards,GS, Pearlstein,RD, Copeland,ML, Hutson,MS, Latone,K, Spiro,A, Pasmanik,G. 6450 Nm Wavelength Tissue Ablation Using a Nanosecond Laser Based on Difference Frequency Mixing and Stimulated Raman Scattering, Opt. Lett., 32, 1426-1428, 2007   DOI Link

Peralta,XG, Toyama,Y, Hutson,MS, Montague,R, Venakides,S, Kiehart,DP, Edwards,GS. Upregulation of Forces and Morphogenic Asymmetries in Dorsal Closure During Drosophila Development, Biophys. J., 92, 2583-2596, 2007  DOI Link

Weiss,BP, Lima,EA, Fong,LE, Baudenbacher,FJ. Paleointensity of the Earth's Magnetic Field Using SQUID Microscopy, Earth and Planetary Science Letters, 264, 61-71, 2007  DOI Link

Eklund,SE, Snider,RM, Wikswo,J, Baudenbacher,F, Prokop,A, Cliffel,DE, Multianalyte Microphysiometry as a Tool in Metabolomics and Systems Biology, J Electroanal Chem, 587: 333-339, 2006  DOI Link

Sai,JG, Walker,G, Wikswo,J, Richmond,A, The IL Sequence in the LLKIL Motif in CXCR2 is Required for Full Ligand Induced Activation of ERK, AKT and Chemotaxis in HL60 Cells, J Biol Chem, 281: 35931-35941, 2006  DOI Link

Shastri,VP, Future of regenerative medicine: Challenges and hurdles, Artificial Organs, 30(10): 828-834 (Invited Paper), 2006  DOI Link

Warnement,MR, Faley,SL, Wikswo,JP, Rosenthal,SJ, Quantum Dot Probes for Monitoring Dynamic Cellular Response: Reporters of T Cell Activation, IEEE Trans Nanobiosci, 5: 268-272, 2006  DOI Link

Xu,XJ, Sy,JC, Shastri,VP , Towards developing surface eroding poly(alpha-hydroxy acids, Biomaterials, 27: 3021-3030, 2006  DOI Link

Gattacceca,J, Boustie,M, Weiss,BP, Rochette,P, Lima,EA, Fong,LE, Baudenbacher,FJ. Investigating Impact Demagnetization Through Laser Impacts and SQUID Microscopy, Geology, 34, 333-336, 2006  DOI Link

Xiao,Y, Guo,M, Parker,K, Hutson,MS. Wavelength-Dependent Collagen Fragmentation During Mid-IR Laser Ablation, Biophys. J., 91, 1424-1432, 2006   DOI Link

Ges,IA, Ivanov,BL, Schaffer,DK, Lima,EA, Werdich,AA, Baudenbacher,FJ, Thin-Film IrOx pH Microelectrode for Microfluidic-Based Microsystems, Biosensors & Bioelectronics, 21: 248-256, 2005  DOI Link

Fong,LE, Holzer,JR, McBride,KK, Lima,EA, Baudenbacher,F, Radparvar,M, High-Resolution Room-Temperature Sample Scanning Superconducting Quantum Interference Device Microscope Configurable for Geological and Biomagnetic Applications, Rev Sci Instrum , 76, 053703, 2005  DOI Link

Walker,GM, Sai,JG, Richmond,A, Stremler,MA, Chung,CY, Wikswo,JP, Effects of Flow and Diffusion on Chemotaxis Studies in a Microfabricated Gradient Generator, Lab on a Chip, 5: 611-618, 2005  DOI Link

Wang,W, Shor,LM, LeBoeuf,EJ, Wikswo,JP, Kosson,DS, Mobility of Protozoa Through Narrow Channels, Appl Environ Microbiol, 71: 4268-4637, 2005  DOI Link

Yang,Z, Shen,W, Rottman,JN, Wikswo,JP, Murray,KT, Rapid Stimulation Causes Electrical Remodeling in Cultured Atrial Myocytes, J Mol Cell Cardiol, 38: 299-308, 2005  DOI Link

Baudenbacher F, Fong LE, Thiel G, Wacke M, Jazbinsek V, Holzer JR, Stampfl A, Trontelj Z., Intracellular axial current in Chara corallina reflects the altered kinetics of ions in cytoplasm under the influence of light, Biophysical J, 88(1):690-697, 2005  DOI Link

Sidorov VY, Woods MC, Baudenbacher P, Baudenbacher F., Examination of Stimulation Mechanism and Strength-Interval Curve in Cardiac Tissue, Am J Physiol Heart Circ Physiol, 289(6):H2602-H615, 2005  DOI Link

Werdich,A, Lima,EA, Ivanov,B, Ges,I, Wikswo,JP, Baudenbacher,FJ, A Microfluidic Device to Confine a Single Cardiac Myocyte in a Sub-Nanoliter Volume on Planar Microelectrodes for Extracellular Potential Recordings, Lab on a Chip, 4: 357-362, 2004  DOI Link

Chancellor,EB, Wikswo,JP, Baudenbacher,F, Radparvar,M, Osterman,D, Heat Conduction Calorimeter for Massively Parallel High Throughput Measurements with Picoliter Sample Volumes, Appl Phys Lett, 85: 2408-2410, 2004  DOI Link

Eklund,SE, Taylor,D, Kozlov,E, Prokop,A, Cliffel,DE, A Microphysiometer for Simultaneous Measurement of Changes in Extracellular Glucose, Lactate, Oxygen, and Acidification Rate, Anal Chem, 76: 519-527, 2004  DOI Link

Prokop,A, Prokop,Z, Schaffer,D, Kozlov,E, Wikswo,JP, Cliffel,D, Baudenbacher,F, NanoLiterBioReactor: Long-Term Mammalian Cell Culture at Nanofabricated Scale, Biomed Microdevices, 6: 325-339, 2004  DOI Link

Rocheleau,JV, Walker,GM, Head,WS, McGuinness,OP, Piston,DW, Microfluidic Glucose Stimulation Reveals Limited Coordination of Intracellular Ca2+ Activity Oscillations in Pancreatic Islets, PNAS, 101:12899-12903, 2004  DOI Link

Holzer JR, Fong LE, Sidorov VY, Wikswo JP Jr, Baudenbacher F., High Resolution Magnetic Images of Planar Wave Fronts Reveal Bidomain Properties of Cardiac Tissue, Biophysical J, 87(6):4326-32, 2004  DOI Link

Eklund,S and Cliffel,DE. Synthesis and Catalytic Properties of Soluble Platinum Nanoparticles Protected by a Thiol Monolayer, Langmuir, 20, 6012-6018, 2004  DOI Link

Baudenbacher,F, Fong,LE, Holzer,JR, Radparvar,M, Monolithic Low-Transition-Temperature Superconducting Magnetometers for High Resolution Imaging Magnetic Fields of Room Temperature Samples, Appl Phys Lett, 82: 3487-3489, 2003   DOI Link

Eklund,SE, Cliffel,DE, Kozlov,E, Prokop,A, Wikswo,JP, Jr., Baudenbacher,FJ, Modification of the Cytosensor TM Microphysiometer to Simultaneously Measure Extracellular Acidification and Oxygen Consumption Rates, Anal Chim Acta, 496:93-101, 2003 93-101, 2003  DOI Link

Invited Reviews and Commentaries

Gray,RA and Wikswo,JP. Cardiovascular Disease: Several Small Shocks Beat One Big One, Nature, 475, 181-182, 2011  DOI Link

Enders,JR, Goodwin,CR, Marasco,CC, Seale,KT, Wikswo,JP, Mclean,JA. Advanced Structural Mass Spectrometry for Systems Biology: Pulling the Needles From Haystacks, Spectroscopy Supp. Curr. Trends Mass Spectrometry, July, 18-23, 2011  Full Text

Kliman,M, May,JC, McLean,JA. Lipid Analysis and Lipidomics by Structurally Selective Ion Mobility-Mass Spectrometry, Biochimica Et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1811, 935-945, 2011  DOI Link

Seale,K, Janetopoulos,C, Wikswo,J. Micro-Mirrors for Nanoscale Three-Dimensional Microscopy, Acs Nano, 3, 493-497, 2009   DOI Link

Addae-Mensah,KA and Wikswo,JP. Measurement Techniques for Cellular Biomechanics In Vitro, Experimental Biology and Medicine, 233, 792-809, 2008  DOI Link

Huang,S and Wikswo,J, Dimensions of Systems Biology, Reviews of Physiology, Biochemistry and Pharmacology, Amara,SG, Bamberg,E, Gudermann,T, Hebert,SC, Jahn,R, Lederer,WJ, Lill,R, Miyajima,A, Offermanns,S, Eds, 81-104, 2006  DOI Link

Wikswo,JP, Prokop,A, Baudenbacher,F, Cliffel,D, Csukas,B, Velkovsky,M, The Engineering Challenges of BioNEMS: The Integration of Microfluidics, and Micro- and Nanodevices, Models, and External Control for Systems Biology, IEE Proceedings Nanobiotechnology, 153: 81-101, 2006  DOI Link

Methods Papers and Application Notes

Markov,DA, Lillie,EM, Samson,PC, Wikswo,JP, McCawley,LJ. A Method for Periodic Sterile Sample Collection During Continuous Cell Culture in Microfluidic Devices, Lab Chip, http://www.rsc.org/Publishing/Journals/lc/Chips_and_Tips/microfluidic_devices.asp#, 2010

Greene,J, Henderson,JW, Jr., Wikswo,JP. Rapid and Precise Determination of Cellular Amino Acid Flux Rates Using HPLC With Automated Derivatization With Absorbance Detection. Application Note, 5990-3283EN, Agilent Technologies , 2009   Full Text Link

Book Chapters

Schmidt,M and Lipson,H. Age-Fitness Pareto Optimization. In: Genetic programming theory and practice VIII, Riolo,R, McCongahy,T, Vladislavleva,E, eds. Springer, New York, 129-146, 2011   DOI Link

Enders,JR, Kliman,M, Sundarapandian,S, Mclean,JA. Peptide and Protein Analysis Using Ion Mobility-Mass Spectrometry. In: Peptide and Protein Mass Spectrometry in Drug Discovery, Gross,ML, Chen,G, Pramanik,B, eds. J. Wiley & Sons, 139-174, 2011  DOI Link

McLean,JA, Schultz,JA, Woods,AS. Ion Mobility-Mass Spectrometry for Biological and Structural Mass Spectrometry. In: Electrospray and MALDI mass spectrometry: fundamentals, instrumentation, practicalities, and biological applications, Cole,RB, ed. Wiley, Hoboken, N.J., 411-439, 2010

May,JC and McLean,JA. The Conformational Landscape of Biomolecules in Ion Mobility-Mass Spectrometry. In: Ion Mobility Spectrometry-mass Spectrometry: Theory and applications, Wilkins,CL and Trimpin,S, eds. CRC Press, Boca Raton, FL, 327-343, 2010

Mclean,JA, Fenn,LS, Enders,JR. Structurally Selective Imaging Mass Spectrometry by Imaging Ion Mobility-Mass Spectrometry. In: Mass Spectrometric Imaging: History, Fundamentals and Protocols, Sweedler,JV and Rubakhin,SS, eds. Humana Press, New York, 363-383, 2010  DOI Link

Wikswo,JP and Roth,BJ. Virtual Electrode Theory of Pacing. In: Cardiac bioelectric therapy: Mechanisms and practical implications, Efimov,I, Kroll,M, Tchou,P, eds. Springer, 283-330, 2009   DOI Link

Rocheleau,JV and Piston,DW. Combining Microfluidics and Quantitative Fluorescence Microscopy to Examine Pancreatic Islet Molecular Physiology. In: Methods in Cell Biology, Correia,JJ and Detrich,HW, eds. Elsevier, 71-92, 2008   DOI Link

Jayagopal,A, Shastri,VP, Nanoengineering of Drug Delivery Systems, in Nanoparticulate Drug Delivery Systems, Thassu,D, Deleers,M, Pathak,Y, Eds., Informa Heathcare, NY, Chp. 7, 99-110, 2007

Jayagopal,A, Shastri,VP, Nanoscale Engineering of Biomaterial Surfaces, in Nanotechnologies for the Life Sciences, Volume 8: Nanotechnologies for Tissue, Cell and Organ Engineering, Kumar,C, Ed., Wiley-VCH , Chapter 12, 461-505, 2006  DOI Link

Eklund,SE, Kozlov,E, Taylor,DE, Baudenbacher,F, Cliffel,DE, Real-Time Cell Dynamics With a Multianalyte Physiometer, in NanoBiotechnology Protocols, Rosenthal,S and Wright,D, eds. Humana Press, Totawa, NJ, 209-223, 2005  DOI Link

Patents

Wikswo,JP, Baudenbacher,FJ, Cliffel,DE, Haselton,FR, LeBoeuf,EJ, Prokop,A, Reiserer,RS, Stremler,MA, Bioreactors With Multiple Chambers, Pat.No. 7,977,089 B2, July 12, 2011   Full Text Link

Seale,KT, Reiserer,RS, Wikswo,JP, Photolithographed Micro-Mirror Well for 3D Tomogram Imaging of Individual Cells, US Pat.No. 7,974,003 B2, July 5, 2011   Full Text Link

Wikswo,JP, Baudenbacher,FJ, McGuinness,O, Device and Methods for Monitoring the Status of at Least One Cell, US Pat.No. 7,981,649 B2, July 19, 2011   Full Text Link

Wikswo,JP, Baudenbacher,FJ, Prokop,A, LeBoeuf,EJ, Chung,CY, Cliffel,DE, Haselton,FR, Hofmeister,WH, Lin,CP, McCawley,LJ, Reiserer,RS, Stremler,MA, Capillary Perfused Bioreactors With Multiple Chambers, US Pat.No. 8,003,378 B2, Aug. 23, 2011   Full Text Link

Cliffel,D, Baudenbacher,FJ, Wikswo,JP, Eklund,S, Balcarcel,RR, Gilligan,JM, Device and Methods for Detecting the Response of a Plurality of Cells to at Least One Analyte of Interest, US Pat.No. 7,713,733 B2, May 11, 2010   Full Text Link

Baudenbacher,FJ, Wikswo,JP, Balcarcel,RR, Cliffel,D, Eklund,S, Gilligan,JM, McGuinness,O, Monroe,T, Prokop,A, Stremler,MA, Werdich,AA, Apparatus and Methods for Monitoring the Status of a Metabolically Active Cell, US Pat.No. 7,704,745 B2, Apr. 27, 2010   Full Text Link

Wikswo,JP, Baudenbacher,FJ, Haselton,FR, Hofmeister,WH, Lin,CP, McCawley,LJ, Stremler,MA, Weaver,A, Bioreactors With Substance Injection Capacity, US Pat.No. 7,790,443 B2, Sept. 7, 2010   Full Text Link

Wikswo,JP, Baudenbacher,FJ, Prokop,A, LeBoeuf,EJ, Chung,CY, Cliffel,DE, Haselton,FR, Hofmeister,WH, Lin,CP, McCawley,LJ, Reiserer,RS, Stremler,MA, Capillary Perfused Bioreactors With Multiple Chambers, US, Patent Number - 7,534,601 B2, 2009  Full Text Link

Wikswo,JP, Baudenbacher,FJ, McGuinness,O, Device and Methods for Monitoring the Status of at Least One Cell, US Patent Number - 7,435,578 B2, 2008   Full Text Link

Conference Proceedings

Davis,LM, Canfield,BK, Germann,JA, King,JK, Robinson,WN, Dukes III,AD, Rosenthal,SJ, Samson,PC, Wikswo,JP. Four-Focus Single-Particle Position Determination in a Confocal Microscope. In: Single molecule spectroscopy and imaging III, Proceedings SPIE, Vol. 7571, Enderlein,J and Gryczynski,Z, eds. SPIE, Bellingham, WA, 757112 2010

Seale,K, Armstrong,P, Wikswo,J. The Systems Biology and Bioengineering Undergraduate Research Experience at Vanderbilt University. Preparing the Engineers and Technologists of Tomorrow, ASEE Southeastern Section Annual Conference, Marietta, GA, http://155.225.14.146/asee-se/proceedings/ASEE2009/papers/PR2009098SEA.PDF, 2009

Ges,IA and Baudenbacher,FJ. Amperometric Glucose Sensor for Real Time Extracellular Glucose Monitoring in Microfluidic Device. In: Nanotechnology 2008: Technical proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show: Boston, June 1-5, Romanowicz,BF and Laudon,M, eds. Nano Science and Technology Institute; CRC Press, Boston, MA; Boca Raton, FL, USA, 253-256, 2008

Kim,EGR, Sivasubramaniam,P, Wikswo,JP, Seale,KT. Differential Optical Flow for Automated Cell Motility. In: Micro total analysis systems 2008: proceedings of the ?TAS 2008: Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences, Locascio,LE, ed. Chemical and Biological Microsystems Society, San Diego, CA, 1831-1833, 2008

Prokop,A, Prokop,Z, Schaffer,D, Kozlov,E, Wikswo,JP, Cliffel,D, Baudenbacher,F. NanoLiterBioReactor: Monitoring of Long-Term Mammalian Cell Physiology at Nanofabricated Scale. In: Biological and Bioinspired Materials and Devices, Aizenberg,J, Orme,C, Landis,WJ, Wang,R, eds. MRS, W9.5/O5.5 2004