Vanderbilt Institute of Chemical Biology

 

 

Something new is
happening at the VICB

 

 

 

 

 

 

 

 

 

 

VICB Discoveries

Infectious Disease Mechanisms and Antimicrobial Drug Discovery

 

Increasing Bacterial Virulence by Metabolic Collaboration

October 20, 2014

 

Targeting Flu Through A Host Protein

August 20, 2014

 

Two-Component System Cross-Talk in the Anthrax Pathogen

April 4, 2014

 

Exploring the Dynamics of Proton-Driven Multidrug Transporter

December 16, 2013

 

Clostridium difficile Hijacks Cellular Production of Reactive Oxygen Species to Kill Its Host

November 13, 2013

 

Combatting Antibiotic Drug Resistance

September 26, 2013

 

Dissecting the Molecular Pathogenesis of Bone Infection by Staphylococcus aureus

July 2, 2013

 

Discovery of Antibacterial Activity Targeting Fermenting Staphylococcus aureus

May 7, 2013

 

Anatomy Of A Neurotoxin

April 9, 2013

 

Biomarking Infection with BSI

April 1, 2013

 

Combatting Bacteria by Manganese Sequestration

March 4, 2013

 

Metabolic Response to Antibiotic Resistance

February 1, 2013

 

Visualizing Infection

July 18, 2012

 

Human Versus Staphylococcus: The Fight for Iron

January 5, 2011

 

How a Bacterial Toxin Causes Diarrhea

August 6, 2010

 

Key to Virulence of Meningitis Bacterium

April 8, 2010

 

Investigating the Mad Cow Prion

March 14, 2010

 

 

Cancer Biology and Cancer Drug Discovery


Signature of Aggressive Colorectal Cancer

November 12, 2014


What Drives Cancer?

July 28, 2014

 

Visualizing Cell Death In Vivo

March 25, 2014

 

A New Approach to Targeting Ras

February 27, 2014

 

A Stapled Peptide Probe of Replication Protein A’s Protein-Protein Interactions

December 12, 2013

 

Targeting Glioblastoma Through Phospholipase D

December 2, 2013

 

Discovery of an Inhibitor of Replication Protein A’s Protein-Protein Interactions

October 30, 2013

 

Windorphen: A New Wnt Signaling Inhibitor

September 23, 2013

 

Discovery of Mcl-1 Inhibitors Offer Hope for New Cancer Therapeutics

January 8, 2013

 

Targeting Cancer Through K-Ras

May 29, 2012

 

Personalizing the Effects of Therapy

January 24, 2012

 

Targeted Imaging Agent Puts the Focus on Cancer

October 12, 2011

 

The Seven Signatures of Triple Negative Breast Cancer

June 24, 2011

 

Stopping Cancer Cell Invasion

February 25, 2011

 

New Tool in the Fight Against Colon Cancer

November 1, 2010

 

Novel Approach to Fight Cancer

September 23, 2010

 

Fighting Cancer with Nanotechnology

July 15, 2010

 

Of Wingless Flies and Cancer

April 26, 2010

 

 

Neuroscience and Neuroscience Drug Discovery

 

Tackling Anxiety

July 21, 2014

 

New Class of Cyclooxygenase Inhibitors with Anti-Anxiety Activity

August 7, 2013

 

A Potassium Channel Activator Possesses Anticonvulsant Activity

June 9, 2013

 

Cholesterol and the Brain

June 19, 2012

 

Nanoscience Meets Drug Discovery

March 7, 2012

 

New Tricks for Some Old Drugs

October 19, 2011

 

 

Therapeutic Discovery – Other Targets

 

Bacteria to the Rescue!

June 30, 2014

 

Antioxidant Therapy Provides Hope for Smith-Lemli-Opitz Syndrome

August 5, 2013

 

A New Drug Discovery Program Targeting Obesity Receives NIH Funding

July 23, 2013

 

New Tool To Combat Heart Disease

December 9, 2011

 

The Search for Novel Drugs Goes Underground

January 14, 2011

 

Drug Discovery Focuses On Fish

February 5, 2010

 

 

Combatting Malaria

 

Honing the Sensitivity of Malaria Diagnosis

May 6, 2014

 

Linking the Sense of Smell to Reproduction in Anopheles gambiae Mosquitoes

February 10, 2014

 

Potassium Channel Inhibition as a New Insecticide Target for Mosquito Control

June 10, 2013

 

Odorant Receptor Expression Directs Behavior in Anopheles gambiae Mosquitoes

May 14, 2013

 

Sniffing out New Ways to Combat Malaria

May 19, 2011

 

On the Scent of the Malaria Mosquito

February 19, 2010

 

 

DNA Replication, Damage, and Repair

 

Identifying the Elusive Protein-DNA Cross-Link

October 22, 2013

 

SV40 Virus Co-Opts the Host DNA Damage Response

April 30, 2013

 

A New Structural Framework for Replication Protein A (RPA)s

January 28, 2013

 

Bypassing A Toxic DNA Adduct: A Look Into The Enzyme Active Site

October 11, 2011

 

A  Closer Look at DNA Replication with iPOND

July 14, 2011

 

AlkD's Novel Approach to DNA Repair

October 29, 2010

 

Prime Time for DNA Replication

August 27, 2010

 

 

Biochemistry

 

Bioengineering

 

Constructing a Biosynthetic Pathway in Reverse

March 28, 2014

 

Harnessing the Circadian Clock to Boost Useful Bioproduction in Cyanobacteria

November 20, 2013

 

 

Lipids

 

Biochemical Collaboration Leads to Novel Biologically Active Lipids

April 25, 2011

 

Are Your Lipids Stressed Out?

January 25, 2010

 

 

Mechanisms of Cytotoxicity

 

Functional Impact of Protein Modification by Lipid Electrophiles

January 30, 2014

 

 

Signaling

 

Exploring the Dynamics of Active Transport
October 10, 2014

 

A Global View of S-Sulfenylation
September 9, 2014

 

Energetics of the Activated Receptor-G Protein Interaction

December 13, 2013

 

Probing Arrestin Conformation

November 5, 2012

 

New Insights into G-Protein-Receptor Coupling

June 10, 2011

 

 

Proteins

 

Bromide Ion is Essential for Life

June 24, 2014

 

Bringing Order to Chaos

April 25, 2014

 

Sulfilimine Cross-Links: A Key to Tissue Evolution

January 2, 2014

 

Key to Collagen Cross-Links

August 28, 2012

 

Protein Symmetry by Design

October 18, 2011

 

Backscattering Interferometry - Shining Light on Protein-Ligand Interactions

March 28, 2011

 

 

Transcription

 

How MicroRNAs Modulate Gene Expression

April 12, 2013

 

Survival Advantage Conveyed by Non-Optimal Codon Usage

February 26, 2013

 

 

 

Novel Chemistry

 

Reversing Polarity to Conserve Chirality

June 24, 2010

 

Nature's Approach to Solar Power

March 3, 2010

Recent News

Johnson to Partner with Brazilian Researchers

November 12, 2014

 

Staph ‘Gangs’ Share Nutrients During Infection: Study

October 17, 2014

 

Zwiebel's Research Featured in Bill Gates Newsletter

October 14, 2014

 

Schizophrenia ‘Switches’ Discovered

September 12, 2014

 

VU Study Creates New Road Map for Cellular Activity

September 8, 2014

 

Foundation Grants Bolster Autism, Dystonia Research

September 4, 2014


Vanderbilt Team Makes Colon Cancer Discovery

July 22, 2014

 

Vanderbilt Licenses First Technology of New Fiscal Year to HTS Startup

July 15, 2014

 

Pietenpol Named to IOM Cancer Policy Forum

July 10, 2014

 

Engineered Probiotics Prevent Obesity in Mice

June 30, 2014

 

McLean Named ‘Thought Leader’ for Ion Mobility Mass Spectrometry Research

June 23, 2014

 

Pharmacology Reached New Heights on Hamm’s Watch

June 13, 2014

 

Caprioli Is Recipient of 2014 ASMS Award

June 6, 2014

 

VU Investigators Confirm Bromine’s Critical Role in Tissue Development

June 5, 2014

 

Marnett Named to Lead VUMC Research

May 30, 2014

 

Repair Protein’s DNA Recognition Motif

May 29, 2014

 

Mchaourab, McLean, Wright Honored with Endowed Chairs

May 8, 2014

 

A Bug Repellent That Could Save Lives

May 5, 2014

 

Team Finds Way to Explore "Super Family’ of Enzymes"

April 24, 2014

 

Micro-Organs to Shape Future of Personalized Medicine

April 21, 2014

 

Channel Drug Restores Glucose Balance

April 16, 2014

 

Anthrax Bacteria’s Signaling Systems

April 15, 2014

 

Rosenthal Named Winner of 2014 SEC Faculty Achievement Award

April 11, 2014

 

VU Making Plans for $50M Academic Venture Fund

April 8, 2014

 

From R&D to Rx: Academia & Industry Pool Efforts to Speed Discovery of Personalized New Drugs

April 1, 2014

 

Shifting Evolution into Reverse Promises Cheaper, Greener Way to Make New Drugs

March 24, 2014

 

Small Molecule Protects Kidney Filters

March 20, 2014

 

Vanderbilt Awarded $16.5 Million Agreement to Determine How Toxic Agents Affect Human Cells

March 3, 2014

 

Dismantling Staph’s Drug Resistance

March 3, 2014

 

ASPET Honors Lindsley’s Pharmacology Research

February 27, 2014

 

Antioxidants Promising for Rare Disorder

February 7, 2014

 

Mosquito Sperm Have a Sense of Smell

February 4, 2014

 

Untangling RAS, An “Undruggable” Cancer-Causing Protein

January 28, 2014

 

Alex Brown Honored With Endowed Chair

January 27, 2014

 

VICC Receives $100K Ovarian Cancer Research Grant

January 23, 2014

 

New Approach May Halt Glioblastoma’s Ability to Grow

January 17, 2014

 

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The Vanderbilt Institute of Chemical Biology, 896 Preston Building, Nashville, TN 37232-6304, phone 866.303 VICB (8422), fax 615 936 3884
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