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Clinical Science Brown Bag series - CANCELLED
December 6, 2016

Andrew Tomarken

Department of Psychology

Vanderbilt University

12:10pm

Wilson Hall Room 316

Title & Abstract TBA


CCN Brown Bag Series
December 7, 2016

Leslie Blaha Ph.D.

Pacific Northwest National Laboratory

https://aim.pnnl.gov/staff/leslie-blaha

12:10pm

Wilson Hall Room 113

Towards Real-Time Cognitive Model Based Monitoring for Adaptive Decision Support

In applied settings, cognitive models serve a critical role bridging theory and practice, bridging the laboratory and the real world.  There is particularly strong potential for using models as these bridges in the design of adaptive human-computer interfaces to support complex, dynamic decision making. Simultaneously, these dynamic decision-making environments both offer rich behaviors for study and challenge our ability to assess cognitive performance. In this talk, I will argue that leveraging cognitive models for measurement is (1) critical to understanding performance in such complex settings and (2) critical to developing the desired adaptive systems responsive to user performance interpreted through the cognitive models.  I will review initial steps we have taken to advance the use of models as measurement tools, including a new technique for real-time model parameter estimation. I will explore how dynamic multitasking requires potential extensions of discrete decision making models to more continuous decision monitoring while raising questions for how to model task switching. I will show how early modeling of eye-hand coordination on touchscreens indicates how interaction properties shape the dynamics of both movements.  Throughout this talk, I will raise important questions to challenge cognitive modeling research to continue bridging the laboratory and applied settings.

Speaker Bio: (http://aim.pnnl.gov).  She holds a B.Ph. in Interdisciplinary Studies (focus in Cognitive Science) and a B.A. in Mathematics & Statistics from Miami University. She completed her Ph.D. in 2010 at Indiana University-Bloomington with a joint degree in Psychology and Cognitive Science.  Prior to joining PNNL she led an in-house basic research team at the Battlespace Visualization Branch of the Air Force Research Laboratory. For more on her research, visit http://sai.mindmodeling.org.

 


Neuroscience Brown Bag Series
December 8, 2016

Maureen Virts

Department of Hearing & Speech (Ramachandran Lab)

Vanderbilt University School of Medicine

12:10pm

Wilson Hall Room 316

Spatial Release of Masking in Macaques and its Neuronal Correlates

Tones spatially separated from maskers are detected at lower sound levels than those colocalized with maskers (spatial release from masking, SRM). SRM has been well explored in humans but not in animal models. SRM, when measured in azimuth, may index temporal processing. We hypothesized that macaques would show significant SRM in azimuth, similar to humans, and that SRM would be worse after noise induced hearing loss in a manner correlated with ribbon synaptopathy, but not outer hair cell loss. We measured SRM for tones (0.5 – 32 kHz) and synthetic human vowels in normal and hearing impaired macaques for spatial separations between signal and masker of  0Ëš, 45Ëš, or 90Ëš in azimuth. Signal detection thresholds were highest when signal and noise were colocalized and lower when the noise was separated from the tone (SRM), consistent with results in humans. SRM was not observed in macaques with hearing loss at frequencies where synaptopathy was observed, even though masked thresholds were higher than tone thresholds. Neuronal responses measured from the inferior colliculus (IC) simultaneously with behavior showed a strong neuronal correlate of SRM. These results suggest that SRM may be a good test for synaptopathy. Supported by NIH-NIDCD T35DC0008763 and R01 DC011092.


Vanderbilt Vision Training Seminar
December 9, 2016

Rob Harrigan

Department of Electrical Engineering (Landman Lab)

Vanderbilt School of Engineering

Friday, 12/9/16

12:00pm

Langford-MRB 4

Room 11455

"Structural-Functional Relationships Between Eye Orbital Imaging Biomarkers and Clinical Visual Assessments"


Optic neuritis (ON) is the most common presenting symptom in MS, and in long standing MS, evoked potential studies show evidence of optic nerve involvement in 90% of patients. The post-mortem optic nerve is atrophic in patients with remote ON and to a lesser extent in MS patients without ON. There is currently little understanding of the relationship between disease severity and function with measures of eye and optic nerve morphology and structure. This research investigated this relationship in a cohort of over 800 patients with MS scanned longitudinally. Orbital magnetic resonance imaging (MRI) were retrieved and labeled in 3D using multi-atlas label fusion. Based on the 3D structures, both traditional radiology measures (e.g., Barrett index, volumetric crowding index, optic nerve length) and novel volumetric metrics were computed. Using stepwise regression and random effects models, the associations between imaging-derived structural metrics and clinical metrics of disease stage and severity are investigated.


**Compliments of David Calkins, PhD - Lunch will be served**


Documentary and discussion: incarceration and mental health
December 11, 2016

Physicians for Human Rights would like to invite you to a documentary screening & discussion about mental health and incarceration in America. We will watch "The Released," a Frontline documentary as described below:

"This year, hundreds of thousands of prisoners with serious mental illnesses will be released into communities across America, the largest exodus in the nation’s history. Typically, mentally ill offenders leave prison with a bus ticket, $75 and two weeks worth of medication. Within eighteen months, nearly two-thirds are re-arrested. In this follow-up to the groundbreaking film The New Asylums, FRONTLINE examines what happens to the mentally ill when they leave prison and why they return at such alarming rates."

We hope you'll join us for a night of good discussion! Pizza will be provided for those who RSVP.


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