Tissue/Serum Proteomics Core

 
Offers a variety of services in order to determine the proteomic profiles of tissue, serum, and other biological fluids using MALDI mass spectrometry.  Investigators work closely with Core personnel in order to design the experiment that will best answer the scientific questions being posed.  The typical study involves examining protein changes between two experimental groups; e.g., control vs. diseased or treated vs. nontreated. The services offered by the Tissue/Serum Proteomics Core include tissue profiling, tissue imaging, 1D and 2D robotic biofluid fractionation and protein profiling, and multidimensional LC-MS/MS “shotgun” proteomics analysis of biofluids and tissue homogenates.  In addition, various biocomputational services are offered in conjunction with data acquisition, including biostatistical comparisons of sample groups and image processing.
 
Director: Richard Caprioli
Website: http://www.mc.vanderbilt.edu/root/vumc.php?site=msrc/tissuecore