Small Molecule NMR Core

The Small Molecule NMR Facility is comprised of four Bruker NMR spectrometers operating at 600, 500, 400 and 300 MHz.

The 300 MHz instrument is equipped with a 7 Tesla Oxford magnet which is controlled by a Bruker DPX-300 console. Although this spectrometer is mainly used for routine 1H and 13C NMR experiments, it can also perform standard two-dimensional (2D) experiments such as COSY, DQF-COSY, NOESY, TOCSY, HMQC and HMBC.

The 400 MHz instrument is equipped with an 9.4 Tesla Oxford magnet which is controlled by a Bruker AV-400 console. This spectrometer is mainly used for the acquisition of standard two-dimensional (2D) experiments such as COSY, DQF-COSY, NOESY, TOCSY, HMQC and HMBC since the BBI probe configuration offers superior 1H sensitivity compared to the QNP probe.

The 500 MHz instrument is equipped with an 11.7 Tesla Oxford magnet which is controlled by a Bruker DRX-500 console. This spectrometer is mainly used for the acquisition of standard two-dimensional (2D) experiments such as COSY, DQF-COSY, NOESY, TOCSY, HMQC and HMBC.

The 600 MHz instrument is equipped with a 14.1 Tesla Bruker magnet which is controlled by a Bruker AV-II console. This spectrometer is mainly used for LC-SPE-NMR experiments where acquisition of standard one and two-dimensional (2D) experiments such as COSY, DQF-COSY, NOESY, TOCSY, HMQC and HMBC are used to elucidated structures of small quantities of compounds.

 

Contact: Donald Stec—Director
Phone: 615-322-6704
Email: donald.f.stec@vanderbilt.edu

 

Markus Voehler—Director of Operations
Phone: 615-342-1573
Email: m.voehler@vanderbilt.edu

 

Website: sitemason.vanderbilt.edu/annmr