Proteomics Core

Provides state-of-the-art instrumentation and expertise in analytical proteomics, proteome profiling, and imaging to Vanderbilt researchers.  Instrumentation is available for protein and peptide separations by 2D-gel electrophoresis and multidimensional high performance liquid chromatography (LC).

Proteins and peptides of interest are processed and subjected to mass spectral (MS) analysis, and protein identifications are made based on a comparison of MS data with sequence information from genomic, protein, and EST databases.  Proteome profiling and imaging in frozen tissue sections are done by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) MS.  Proteomics Laboratory staff provide consultation on experimental design and sample preparation.

Director: Kevin Schey
Co-Associate Director: David Friedman
E-Mail: david.friedman@vanderbilt.edu
Co-Associate Director: Hayes McDonald
E-Mail: hayes.mcdonald@vanderbilt.edu
Website: http://www.mc.vanderbilt.edu/root/vumc.php?site=msrc/proteomics_core

Faculty Advisory Committee Members (2012-2013):
Roger Colbran (Molecular Physiology & Biophysics)
David Cortez (Biochemistry)
Timothy Cover (Infectious Disease)
Scott Hiebert (Cancer Center)
Andrew Link (Pathology, Microbiology & Immunology)
Larry Marnett (Institute for Chemical Biology)
Richard Peek (Digestive Disease Research Center )

Advisory Committee Meetings:
April 2, 2013
August 26, 2010