Monoclonal Antibody Core

The Vanderbilt Monoclonal Antibody Core (VMAC) operates under the auspices of the Vanderbilt Institute of Chemical Biology. Core personnel are experienced in the design, development, and analysis of a wide range of high-throughput, cell-based, reporter, and immunological assays used to generate and characterize monoclonal antibodies. The Core performs rat and mouse immunizations and test bleeds. It also produces monoclonal antibodies by performing hybridoma fusions, subcloning hybridomas, and scaling up hybridoma antibody production in tissue culture. The Core purifies monoclonal antibodies and also has the capability to conjugate these antibodies to reporter molecules, which are used in a wide variety of immunoassays. The Core also assists in the development of immunoassays to detect antigens or antibodies in biopsies or other biological samples.

We also sponsor the Vanderbilt Antibody Repository, in order to make Vanderbilt antibodies available to the Vanderbilt community at nominal prices. These antibodies are generated by Vanderbilt investigators and/or the VMAC and characterized in detail. Information on each is collected, displayed, and validated by the VMAC and/or Vanderbilt investigators.

 

Contact: Albert Reynolds—Executive Director
Phone: 615-343-9532
Email: al.reynolds@vanderbilt.edu

 

Robert Carnahan—Director
Phone: 615-322-5623
Email: robert.carnahan@vanderbilt.edu

 

Website: mc.vanderbilt.edu/vmac