Genome Technology Core

Vanderbilt University Medical Center has invested in a next-generation DNA sequencing platform (Illumina Genome Analyzer). This new instrument has the capability of producing up to a gigabase of DNA sequence per run and offers a broad range of scientific applications including microbial genome re-sequencing, targeted gene re-sequencing, whole transcriptome analysis, and chromatin immunoprecipitation followed by sequencing (ChIP-Seq). This new resource will greatly expand scientific opportunities for many investigators and should enhance competitiveness for extramural funding.

This sequencing technology is available through a newly created shared resource called the Genome Technology Core (GTC) operated jointly by three existing core facilities: the Vanderbilt Microarray Shared Resource, the Vanderbilt DNA Sequencing Facility, and the Computational Genomics Core in the Center for Human Genetics Research. The core welcomes applications for projects designed to fully develop and utilize this technology. Because this instrument represents a substantial investment by the Medical Center, faculty in the School of Medicine will have priority access; however, faculty from across Vanderbilt campus are encouraged to submit project applications. Projects will be evaluated based on several criteria including feasibility, scientific impact and anticipated benefits for obtaining extramural funding. The costs of these new services will be determined after the instrument has been implemented and protocols adopted.

Contact Christie Ingram for the project application format and sample requirements. Applications are to be submitted via e-mail to Ms. Ingram.

Contact: Christie Ingram (2-4231)