chemistry student in lab Slide 1

Cell Imaging Shared Resource (CISR)

Supports the full range of modern microscopy and digital imaging capabilities in order to enable and accelerate research that would otherwise be reduced in quantity and quality. Currently over 200 research groups use the facilities and services of the Resource, which maintains an active development program to keep the instrumentation and systems current, functional, accessible, and easy to use.  CISR currently provides facilities for both optical and electron microscopy; there are six confocal microscopes, one line-scanning microscope, two 2-photon-excitation microscopes, and four advanced wide-field microscopes as well as a Phillips CM-12 120keV Transmission Electron microscope system.

The laboratory is fully equipped to carry out numerous aspects of “routine” as well as specialized electron microscopy. Included in the specialized services available through the resource are: 1) preparative techniques, such as embedding and sectioning, critical point drying, high-resolution low angle and rotary shadowing, and cryo-EM; 2) research techniques, such as immuno- and enzyme-cytochemistry, autoradiography, and whole-mount microscopy; and 3) analytical techniques, such as on- and off-line microcomputer based systems for image processing, pattern analysis, and 3-D reconstruction.

Scientific Director: Dave Piston

Director: Sam Wells

Co-Director – Electron Microscopy: Jay Jerome


Faculty Advisory Committee Memebers (2012-2013):
Elisabeth Dykens (Kennedy Center)
Jim Goldenring (Surgical Sciences)
Scott Hiebert (Cancer Center)
David Kosson (Civil & Environmental Engineering)
Mark Magnuson (Stem Cell Biology)
Richard Peek (Digestive Disease Research Center)
Al Powers (Diabetes Center)
Jeffrey Schall (Vision Research Center)
David Wasserman (Mouse Metabolic Phenotyping Center)
Chris Wright (Program in Developmental Biology)

Advisory Committee Meetings:
June 5, 2013
August 31, 2010