Journal Articles
2006-2009
Russ PK, Kupperman AI, Presley SH, Haselton FR, Chang MS. (2009) "Bves Overexpression in Trabecular Meshwork Cells Inhibits RhoA Signaling." Invest Opthalmol Vis Sci, epub ahead of print [html]
Soman CP, Giorgio TD. (2009) "Sensitive and multiplexed detection of proteomic antigens via quantum dot aggregation." Nanomedicine: Nanotechnology, Biology and Medicine, epub ahead of print [pdf]
Jayagopal A, Su YR, Blakemore JL, Linton MF, Fazio S, Haselton FR. (2009) "Quantum dot mediated imaging of atherosclerosis." Nanotechnology, epub ahead of print [pdf]
Sewell SL, Giorgio TD. (2009) "Synthesis and enzymatic cleavage of dual-ligand quantum dots." Materials Sci & Eng C, 29: 1428-1432. [pdf]
Soman CP, Giorgio TD. (2009) "Kinetics of molecular recognition mediated nanoparticle self-assembly." Nano Res, 2:78-84. [pdf]
Smith RA, Giorgio TD. (2008) "Quantitative measurement of multifunctional quantum dot binding to cellular targets using flow cytometry." Cytometry A, 75(5):465-474. [pdf]
Salaklang J, Steitz B, Finka A, O'Neil CP, Moniatte M, van der Vlies AJ, Giorgio TD, Hofmann H, Hubbell JA, Petri-Fink A. (2008) "Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context." Angew Chem Intl Ed, 47(41):7857-60. [pdf]
Smith RA, Sewell SL, Giorgio TD. (2008) "Proximity-activated nanoparticles: in vitro performance of specific structural modification by enzymatic cleavage." Int J Nanomedicine, 3(1): 95-103. [pdf]
Soman CP, Giorgio TD. (2008) "Quantum dot self-assembly for protein detection with sub-picomolar sensitivity." Langmuir, 24(8):4399-404. [pdf]
Lipski AM, Pino CJ, Haselton FR, Chen IW, Shastri VP. (2008) "The effect of silica nanoparticle-modified surfaces on cell morphology, cytoskeletal organization and function." Biomaterials 29(28): 3836-46. [pdf]
Jayagopal A, Stone GP, Haselton FR. (2008) "Light-guided surface engineering for biomedical applications." Bioconjug Chem 19(3): 792-6. [pdf]
Jayagopal A, Russ PK, Haselton FR. (2007) "Surface engineering of quantum dots for in vivo vascular imaging." Bioconjug Chem 18(5): 1424-33. [pdf]
Stone GP, Wetzel JD, Russ PK, Dermody TS, Haselton FR. (2006) "Autonomous reovirus strain classification using filament-coupled antibodies." Ann Biomed Eng 34(11): 1778-85. [pdf]
Stone GP, Lin KS, Haselton FR. (2006) "Adaptive virus detection using filament-coupled antibodies." J Biomed Opt 11(3): 34012. [pdf]
Kuhn SJ, Hallahan DE, Giorgio TD. (2006) "Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system." Ann Biomed Eng, 34: 51-58. [pdf]
Kuhn SJ, Finch SK, Hallahan DE, Giorgio TD. (2006) "Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix." Nano Lett, 6: 306-312. [pdf]
2001-2005
Harris SS, Giorgio TD. (2005) "Convective flow increases lipoplex delivery rate to in vitro cellular monolayers." Gene Therapy, 12: 512-520. [pdf]
Pino CJ, Haselton FR, Chang MS. (2005) "Seeding of corneal wounds by epithelial cell transfer from micropatterned PDMS
contact lenses." Cell Transplant 14(8): 565-71. [html]
Stone GP, Mernaugh R, Haselton FR. (2005) "Virus detection using filament-coupled antibodies." Biotechnol Bioeng 91(6): 699-706.
Ghosn B, Haselton FR, Gee KR, Monroe WT. (2005) "Control of DNA hybridization with photocleavable adducts." Photochem Photobiol 81(4): 953-9.
Chang MS, Schneider C, Roberts RL, Shappell SB, Haselton FR, Boeglin WE, Brash AR. (2005) "Detection and subcellular localization of two 15S-lipoxygenases in human cornea." Invest Ophthalmol Vis Sci 46(3): 849-56.
Smith RA, Giorgio TD. (2004) "Quantitation and kinetics of CD51 surface receptor expression: implications for targeted delivery." Ann Biomed Eng, 32: 635-644. [pdf]
Smith RA, Giorgio TD. (2004) "Cell-based screening: a high throughput flow cytometry platform for identification of cell-specific targeting molecules." Comb Chem High Throughput Screen, 7: 141-151.
Wyatt SK, Giorgio TD. (2004) "DNA delivery to cells in culture using cationic liposomes." Methods Mol Biol, 245: 83-94.
Giorgio TD, Wyatt SK. (2004) "DNA delivery to cells in culture using PNA clamps." Methods Mol Biol, 245: 53-66.
Stremler MA, Haselton FR, Aref H. (2004) "Designing for chaos: applications of chaotic advection at the microscale." Philos Transact A Math Phys Eng Sci 362(1818): 1019-36.
McQuain MK, Seale K, Peek J, Fisher TS, Levy S, Stremler MA, Haselton FR. (2004) "Chaotic mixer improves microarray hybridization." Anal Biochem 325(2): 215-26.
McQuain MK, Seale K, Peek J, Levy S, Haselton FR. (2003) "Effects of relative humidity and buffer additives on the contact printing of microarrays by quill pins." Anal Biochem 320(2): 281-91.
Monroe WT, Haselton FR. (2003) "Molecular beacon sequence design algorithm." Biotechniques 34(1): 68-70, 72-3.
Hallahan DE, Geng L, Qu C, Scarfone S, Giorgio T, Donnelly E, Gao X, Clanton J. (2003) "Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels." Cancer Cell, 3: 63-74.
Pfeiffer S, Zorn GL, Zhang JP, Farley SM, Giorgio TD, Robson SC, Azimzadeh AM, Pierson RN. (2003) "Hyperacute lung rejection in the pig-to-human model: platelet receptor inhibitors synergistically modulate complement activation and lung injury." Transplantation, 75: 953-959.
Banks GA, Roselli RJ, Chen R, Giorgio TD. (2003) "A model for the analysis of nonviral gene therapy." Gene Therapy, 10: 1766-1775.
Russ PK, Gaylord GM, Haselton FR. (2001) "Retinal vascular permeability determined by dual-tracer fluorescence angiography." Ann Biomed Eng 29(8): 638-47.
Hallahan DE, Qu S, Geng L, Cmelak A, Chakravarthy A, Martin W, Scarfone C, Giorgio T. (2001) "Radiation-mediated control of drug delivery." Am J Clin Oncol, 24: 473-480.
2000 and earlier
Davidson MK, Russ PK, Glick GG, Hoffman LH, Chang MS, Haselton FR. (2000) "Reduced expression of the adherens junction protein cadherin-5 in a diabetic retina." Am J Ophthalmol 129(2): 267-9.
James M, Giorgio TD. (2000) "Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells." Mol Ther 1: 339-346.
Monroe WT, McQuain MM, Chang MS, Alexander JS, Haselton FR. (1999) "Targeting expression with light using caged DNA." J Biol Chem 274(30): 20895-900.
Tseng W, Haselton, FR, Giorgio TD. (1999) "Mitosis activates transgene expression of plasmid delivered by cationic liposomes." Biochimica Biophysica Acta, 1445: 53-64.
Russ PK, Davidson MK, Hoffman LH, Haselton FR. (1998) "Partial characterization of the human retinal endothelial cell tight and adherens junction complexes." Invest Ophthalmol Vis Sci 39(12): 2479-85.
Haselton FR, Dworska EJ, Hoffman LH. (1998) "Glucose-induced increase in paracellular permeability and disruption of
beta-receptor signaling in retinal endothelium." Invest Ophthalmol Vis Sci 39(9): 1676-84.
Alexander JS, Jackson SA, Chaney E, Kevil CG, Haselton FR. (1998) "The role of cadherin endocytosis in endothelial barrier regulation: involvement of protein kinase C and actin-cadherin interactions." Inflammation 22(4): 419-33.
Alexander JS, Patton WF, Christman BW, Cuiper LL, Haselton FR. (1998) "Platelet-derived lysophosphatidic acid decreases endothelial permeability in vitro." Am J Physiol 274: H115-22.
Haselton FR, Heimark RL. (1997) "Role of cadherins 5 and 13 in the aortic endothelial barrier." J Cell Physiol 171(3): 243-51.
Tseng W, Haselton, FR, Giorgio TD. (1997) "Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression." J Biol Chem, 272: 25641-25647.
Tseng W, Haselton, FR, Giorgio TD. (1997) "Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression." J Biol Chem, 272(41): 25641-25647.
Montero GA, Giorgio TD, Schnelle KB. (1997) "Supercritical fluid extraction of contaminated soil." J Environ Sci & Health A32: 481-495.
Haselton FR, Woodall JH, Alexander JS. (1996) "Neutrophil-endothelial interactions in a cell-column model of the microvasculature: effects of fMLP." Microcirculation 3(3): 329-42.
Haselton FR, Dworska E, Evans SS, Hoffman LH, Alexander JS. (1996) "Modulation of retinal endothelial barrier in an in vitro model of the retinal microvasculature." Exp Eye Res 63(2): 211-22.
Tseng W, Purvis NB, Haselton FR, Giorgio TD. (1996) "Cationic liposomal delivery of plasmid to endothelial cells measured by quantitative flow cytometry." Biotech and Bioeng, 50: 548-554.
Montero GA, Giorgio TD, Schnelle KB. (1996) "Scale-up and economic analysis for the design of supercritical fluid extraction equipment for remediation of soil." Environ Prog, 15: 112-121.
Giorgio TD, Yek SH. (1995) "The effect of bilayer composition on calcium ion transport facilitated by fluid shear stress." Biochimica Biophysica Acta, 1239: 39-44.
Rozga J, Morsiani E, LePage E, Moscioni AD, Giorgio T, Demetriou AA. (1994) "Isolated hepatocytes in a bioartificial liver: a single group view and experience." Biotech and Bioeng, 43: 645-653.
Purvis NB, Giorgio TD, Stelzer GT, Shults KE. (1994) "Shear-induced platelet activation measured by flow cytometry." Ann NY Acad Sci, 714: 309-311.
Purvis NB, Giorgio TD. (1994) "Cell size and surface area determined by flow cytometry." Ann NY Acad Sci, 714: 306-308.
Nicholson NS, Panzer-Knodle SG, King LW, Taite BB, Keller BT, Tjoeng FS, Engleman VW, Giorgio TD, Feigen LP. (1994) "SC-49992--a potent and specific inhibitor of platelet aggregation." Thromb Res, 74(5): 523-35.
Harris TR, Waters CM, Haselton FR. (1994) "Use of scaling theory to relate measurements of lung endothelial barrier permeability." J Appl Physiol 77(5): 2496-505.
Alexander JS, Blaschuk OW, Haselton FR. (1993) "An N-cadherin-like protein contributes to solute barrier maintenance in cultured endothelium." J Cell Physiol 156(3): 610-8.
Waters CM, Alexander JS, Harris TR, Haselton FR. (1993) "Perilla ketone increases endothelial cell monolayer permeability in vitro." J Appl Physiol 74(5): 2493-501.
Haselton FR, Alexander JS, Mueller SN. (1993) "Adenosine decreases permeability of in vitro endothelial monolayers." J Appl Physiol 74(4): 1581-90.
Haselton FR, Alexander JS. (1992) "Platelets and a platelet-released factor enhance endothelial barrier." Am J Physiol 263: L670-8.
Howell RE, Haselton FR, Mueller SN. (1990) "Angiotensin-converting enzyme kinetics in an endothelial cell column." Am J Physiol 258: L188-94.
Haselton FR, Mueller SN, Howell RE, Levine EM, Fishman AP. (1989) "Chromatographic demonstration of reversible changes in endothelial permeability." J Appl Physiol 67(5): 2032-48.
Howell RE, Lanken PN, Hansen-Flaschen JH, Haselton FR, Albelda SM, Fishman AP. (1989) "Pulmonary extraction of propranolol in normal and oxygen-toxic sheep." J Pharmacol Exp Ther 250(1): 93-9.
Haselton FR, Sperandio PG. (1988) "Convective exchange between the nose and the atmosphere." J Appl Physiol 64(6): 2575-81.
Albelda SM, Sampson PM, Haselton FR, McNiff JM, Mueller SN, Williams SK, Fishman AP, Levine EM. (1988) "Permeability characteristics of cultured endothelial cell monolayers." J Appl Physiol 64(1): 308-22.
Parker RE, Roselli RJ, Haselton FR, Harris TR. (1986) "Effect of perfusate hematocrit on urea permeability-surface area in isolated dog lung." J Appl Physiol 61(4): 1383-7.
Lanken PN, Hansen-Flaschen JH, Sampson PM, Pietra GG, Haselton FR, Fishman AP. (1985) "Passage of uncharged dextrans from blood to lung lymph in awake sheep." J Appl Physiol 59(2): 580-591.
Haselton FR, Parker RE, Roselli RJ, Harris TR. (1984) "Analysis of lung multiple indicator data with an effective diffusivity model of capillary exchange." J Appl Physiol 57(1): 98-109.
Haselton FR, Roselli RJ, Parker RE, Harris TR (1984). "Mathematical models of pulmonary capillary-tissue exchange: limiting vases, sensitivity analysis and moment comparison." Mathematical Biosciences 70:237-263.
Scherer PW, Haselton FR (1982). "Convective exchange in oscillatory flow through the bronchial tree." J Appl Physiol. 53(4):1023-1033.
Haselton FR, Scherer PW (1982). "Flow visualization of steady streaming in oscillatory flow through a bifurcating tube." J Fluid Mech 123:315-333.
Haselton FR, Scherer PW (1980). "Bronchial bifurcations and respiratory mass transport." Science 208(4):69-71.
Scherer PW, Haselton FR (1980). "A network theory of bronchial gas mixing applied to single breath nitrogen washout." Lung 158:201-220.
Scherer PW, Haselton FR (1979) "Convective mixing in tube networks." AIChE J. 25(3):542-544.
Scherer PW, Haselton FR, Hanna L, Stone D (1979). "Growth of hygroscopic aerosols in a model of bronchial airways." J Appl Physiol 47(3):544-550.