News: histone deacetylase

Leukemia’s Chromosomal Break-ups

Friday, June 29th, 2012

Scott Hiebert, Ph.D., has been on a 20-year hunt for the causes of acute myeloid leukemia (AML). When he entered the field in 1992, scientists had identified multiple chromosomal translocations – where two chromosomes break apart and exchange some genetic information – in cells from patients with acute leukemia. At the junctions (breakpoints) where the [...]