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Missing the Mark

Thursday, December 18th, 2014

Since the Pap smear debuted in the 1950s to detect pre-cancerous changes in a woman’s cervix, mortality rates for cervical cancer have dropped by 70 percent, according to the American Cancer Society, making the simple collection of cells from the opening of the cervix perhaps the biggest success story in the history of cancer screening. [...]

A Closer Look

Thursday, December 18th, 2014

From a young age, Scott Sobecki had two loves: medicine and computers. His career path began with the former and gravitated to the latter. Vanderbilt brought them together in one job. Sobecki is the director of the Research Informatics Core at Vanderbilt-Ingram Cancer Center, leading a 25-person team that develops software to aid researchers in [...]

Mining the microbiome

Thursday, December 18th, 2014

Ten-to-one. Cell for cell, they’ve got us outnumbered. And as a group, they have 100 times more genes than we do. Fortunately, these microbes that share our corporeal space are usually on our side. Known collectively as the microbiome, the microbial species that flourish along our mucosal surfaces—the linings of our intestines, mouth and nose, [...]

Up in smoke

Thursday, December 18th, 2014

It has been 50 years since Luther Terry, M.D., the ninth Surgeon General, released the landmark report detailing health risks of smoking. Despite smoking being the single greatest preventable cause of illnesses, disability and death in the United States, it is not considered a chronic health condition. Hilary Tindle, M.D., MPH, aims to change that [...]

A Hopeful Path

Wednesday, May 21st, 2014

Myth: Ovarian cancer does not have symptoms. Fact: It does. Cheri Barrow knows this all too well. In 2007, after months of struggling with severe bloating, reduced appetite, lower pelvic pain and hot flashes, the Elkton, Ky., school teacher went to the doctor and was diagnosed with ovarian cancer. She is currently on her fifth [...]

An Exciting Time

Wednesday, May 21st, 2014

We know that half of all cancer cases are preventable or detectable early, and imaging plays a big role in early detection of tumors. For example, our new lung cancer screening program, just launched in January, provides low-dose CT scans for patients at high risk for lung cancer, one of the deadliest cancers. Ninety percent [...]

A Closer Look

Wednesday, May 21st, 2014

There are two computer screens on the desk of Christine Micheel, Ph.D., one constantly monitoring the Web traffic on MyCancerGenome.org. “I can see how many people are on the website right now and where they are in the world. We get about 1,000 visits every day, and less than half are from the U.S. International [...]

Screening Advances

Wednesday, May 21st, 2014

Finding cancer early may make it easier to treat—and possibly cure. Imaging plays a role in screening to detect breast cancer (mammography) and lung cancer (CT). Vanderbilt has made recent advances in both areas, with the implementation of powerful new breast imaging technology and the launch of a lung cancer screening program. The Vanderbilt Breast [...]

Visualizing Data

Wednesday, May 21st, 2014

      These graphs, called Circos plots, help researchers visualize genomic data. Each plot shows a tumor’s complete genetic sequence. The outer ring represents the genome’s 22 chromosomes plus sex chromosomes X and Y. The middle rings plot where single bases of DNA mutate or where larger sections of DNA are inserted or deleted [...]

Brock family supports promising young researchers

Wednesday, May 21st, 2014

Young cancer researchers at Vanderbilt-Ingram Cancer Center have a new champion in the Brock family. John F. Brock III, chairman and CEO of Coca-Cola Enterprises, his wife, Mary, and their three children, Rebecca, John IV and Major, have established the Brock Family Fellowship, an endowment that supports physicians, postdoctoral students and researchers furthering their training. [...]