Dept. of Biological Sciences, Vanderbilt University
Studying cell polarity during migration & cell division
Cell division (cytokinesis) and directed cell migration (chemotaxis) are two processes that have been implicated in many disease states, including many forms of cancer. Research in my lab is focused on understanding how cells establish and maintain polarity during chemotaxis and also during cytokinesis. Molecular and biochemical approaches are being used to study known signaling and cytoskeletal proteins and also to find new components which regulate cell polarity. Advanced light microscopy is used to visualize these proteins and their localization under various conditions in the living cell.