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David Weaver Associate Director
Charles David "Dave" Weaver, Ph.D. is the Director of the Vanderbilt Institute of Chemical Biology's High-Throughput Screening facility, Co-director of Vanderbilt's Molecular Library Screening Center, and Research Associate Professor of Pharmacology. Weaver received his Ph.D. in Biochemistry from the University of Tennessee, Knoxville, in 1994 and was a postdoctoral fellow in Pharmacology at Vanderbilt University until 1997. In 1997, his interest in applied science led to Dave accepting a position as a Research Investigator in the Neuroscience Department at Bristol-Myers Squibb in Wallingford, CT. There he focused on developing techniques for discovering chemical modulators of potassium channels. Weaver moved to the Lead Discovery Department at Bristol-Myers Squibb in 1999 where he led a team of scientists engaged in drug discovery for ion channel and transporter targets in the areas of neuroscience, genitourinary, cardiovascular and immunological diseases. He was selected to become a member of the senior leadership team of New Leads Biology, the division responsible for the management of Bristol-Myers Squibb's compound collection, Lead synthesis and Hits-to-Leads chemistry group, and Lead Discovery. In 2003 Weaver chose to leave Bristol-Myers Squibb and accepted an offer to develop a high-throughput screening laboratory for the Vanderbilt Institute of Chemical Biology and Research Assistant Professor position in the Department of Pharmacology in the Vanderbilt School of Medicine. Weaver's research continues to focus on development and implementation of technologies to enable the discovery of chemical modulators of a variety of molecular targets and pathways in neuroscience, metabolism, and most recently cancer cell biology.