Selective Reversible Cyclooxygenase-2 Inhibitors

Summary

A method of altering specificity of cyclooxygenase-inhibiting compounds that have a COOH moiety by changing the various COOH containing compounds, such as indomethacin, into ester derivatives or into secondary amide derivatives.

Patent

Patents protecting this technology have been issued in the U.S., Europe, Great Britain, Germany, and France.

U.S. Patent 6,762,182: Converting cox inhibition compounds that are not COX-2 selective inhibitors to derivatives that are COX-2 selective inhibitors

Inventors: 
Lawrence MarnettAmit Kalgutkar
Licensing manager: 
Mike Villalobos

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