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Selective Reversible Cyclooxygenase-2 Inhibitors
A method of altering specificity of cyclooxygenase-inhibiting compounds that have a COOH moiety by changing the various COOH containing compounds, such as indomethacin, into ester derivatives or into secondary amide derivatives.
Patents protecting this technology have been issued in the U.S., Europe, Great Britain, Germany, and France.
Inventors:Lawrence MarnettAmit Kalgutkar