Screening Test for ACE or Vasopeptidase Inhibitor Associated Angioedema

Summary

Angioedema is a life-threatening and unpredictable side effect of angiotensin converting enzyme (ACE) inhibitors and ACE/Neutral endopeptidase (NEP) inhibitors, drugs aimed at reducing cardiovascular mortality associated with a variety of disease states. This technology permits the identification of individuals at risk for developing this angioedemic condition as a result of taking ACE inhibitors or NEP inhibitors. The patents and patent applications claim biological markers, diagnostic methods and kits.

Patents

U.S. Patent 6,586,189: Screening method for PPAR-.gamma. ligands

U.S. Patent 6,887,679: Methods for identifying contradictions to angiotensin converting enzyme inhibitor and/or vasopeptidase inhibitor treatment

Inventors: 
Nancy BrownLaine MurpheyKyung Soo KimMarshall Summar
Licensing manager: 
Mike Villalobos

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