Methods and Compositions to Assess Oxidative Brain Injury

A method to assess oxidative stress in vivo includes the steps of measuring an amount of neuroprostanes in a biological sample before the ex vivo development of neuroprostanes in a sample, comparing the measured amount of neuroprostanes with a control and assessing oxidative stress in vivo based on this comparison. There is also provided a marker for oxidated stress by an increase of neuroprostanes in a biological sample compared to a control sample. A diagnostic tool for determining the presence of a neurodegenerative disease provides for determining an increased amount of neuroprostanes in a biological sample compared to that of a control sample.

Website
U.S. Patent 6,620,800: Methods and compositions to assess oxidative brain injury

Inventors: 
L. Jackson Roberts
Licensing manager: 
Mike Villalobos

Featured Video

Vanderbilt Patent Activity

View Vanderbilt University Patents

CTTC on Twitter