- About CTTC
- News & Events
- Invention Disclosure
A Method for Genetically Engineering Proteins with Cell Membrane Translocating Activity
The invention describes a membrane-translocating peptide sequence (MTS) which facilitates entry of polypeptides and proteins into cells. Also described is an isolated nucleotide sequence encoding the membrane-translocating peptide and a method of using this sequence to genetically engineer proteins with cell membrane permeability. The MTS, and the method of genetically engineering proteins with cell membrane permeability, are useful for polypeptide and protein delivery for human and veterinary applications such as vaccine delivery and cancer therapy.
Inventors:Yao-Zhong LinJohn DonahueMauricio RojasZhongjia Tan