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  1. Immortalized Mouse Epididymal Epithelial Cell Lines

    Summary These cell lines are useful for studying the regulation of tissue-specific gene expression, and may also be used to identify epididymal-specific transcription factors involved in expression of specific ... growth and expression of cytokeratin, a marker of epithelial cells. Additionally, these cells express the androgen receptor as ...

    cttc_admin - 05/31/2023 - 2:07pm

  2. Taking a bite out of Charcot-Marie-Tooth Disease

    ... which means that most of the protein gets trapped within the cell, where it becomes toxic and disease causing. More recently, Sanders ... manager of corporate alliances for Vanderbilt’s Center for Technology Transfer and Commercialization,  attended a global conference ...

    sommers - 03/18/2024 - 1:36pm

  3. The yin and yang of cell signaling

    ... Lawrence Marnett , PhD, and colleagues used CRISPR-Cas9 technology to generate stable knock-outs of LYPLA1 and/or LYPLA2 in mouse neuroblastoma cell lines. Their work, published this month in ...

    sommers - 02/21/2019 - 9:51am

  4. Tech Connect, Vol. 7, Issue 12: Vanderbilt Inventor wins ASPET Award

    ... ASPET said Lindsley was honored for “his pioneering use of technology-enabled synthesis, which led to fundamental and transforming effects ... with a pharmaceutical company regarding the use of a mouse model for chronic beta cell depolarization developed by Mark Magnuson of ...

    steelmk - 07/21/2017 - 3:09pm

  5. Tech Connect, Vol. 7, Issue 20: CTTC attends SEMDA with VU students

    ... Vanderbilt technology earns patent protection One new Vanderbilt technology ... with clinical-stage biopharmaceutical company a for a mouse model developed by former faculty member Eric Neilson in the Department ...

    steelmk - 07/21/2017 - 3:34pm

  6. Tech Connect, Vol. 7, Issue 17: Medical Device Lunch and Learn

    ... Technology Spotlight: “Coffee Ring” ... Laboratory to discuss a new licensing model for licensing mouse strains to for-profit companies with the representative ...

    steelmk - 07/21/2017 - 3:29pm

  7. Anti-inflammatory microparticles for sustained ocular drug delivery

    ... gold standard poly(lactic-co-glycolic acid) (PLGA). Technology Description To overcome these challenges, Vanderbilt ... therapeutic effectively improves visual function in mouse models of multiple ocular diseases (Fig. C).  Stage of ...

    cttc_admin - 02/01/2024 - 12:21pm

  8. Vanderbilt scientists, research translation experts attend CMT Global Research Convention

    ... conference,  Margaret Read , Vanderbilt’s  Center for Technology Transfer and Commercialization  general manager for corporate ... friends in the Carter Lab, translating our data and model cell line work to nervous system cells.” Since then, the CMT Research ...

    sommers - 10/02/2023 - 11:32am

  9. Use of Fluid Shear Stress Treatment to Enhance T Cell Activation

    ... effective in activating all types of T cells.   Technology Description Vanderbilt scientists have pioneered a method ... cancer cells, first in vitro and then in vivo using mouse prostate cancer models.   Patent : WO2023283514 ...

    cttc_admin - 01/18/2024 - 9:10am

  10. Partnership to help bring Zika virus therapy to clinic

    ... announced that it has signed a license agreement to use a cell line expression system developed by Horizon Discovery, a life sciences ...  the isolation of a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. Dubbed ...

    sommers - 09/20/2019 - 2:07pm