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Generation of Neuroprogenitor Cells and Neurons from Human Induced Pluripotent Stem Cells by the Dorsomorphin Analog DMH1
This technology describes a novel methodology wherein human-induced pluripotent stem cells can be differentiated into neural precuror cells using DMH1 (a dorsomorphin analog). Neural progenitor cells can then be further differentiated into tyrosine hydroxylase expressing neurons.
Inventors:Charles HongAaron BowmanKevin EssM. Diana Neely