Carboxylic Acid Amides as Selective COX-2 Inhibitors


A method of treating animals having cancer by administration of secondary amide derivatives of various COOH-containing drugs, such as COOH-containing NSAIDs, for instance, indomethacin.


Patents protecting this technology have been issued in the U.S., Europe, Canada, France, Great Britain, and Germany

U.S. Patent 6,399,647: Amide derivatives for antiangiogenic and/or antitumorigenic use

Lawrence MarnettAmit Kalgutkar
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Mike Villalobos

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