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Assay for Novel Serotonin Transporter Blockers
The mutant SERTs we have developed can provide for a platform to screen for novel modes/molecules interrupting SERT function. As SERT blockers are effective antidepressants, this strategy can lead to novel antidepressant medications. It may also be useful in development of animal models to test antidepressant action in vivo.
Inventors:Randy BlakelyKeith HenryErika Adkins