We have developed a technique to process photolithographically porous silicon heterostructures and photonic crystal architectures, using laser and ultraviolet light exposure and a subsequent alcoholic bath treatment. This technique would be the first method to process directly the optical properties of porous silicon multilayers, heterostructures, and photonic crystal architectures.
The present invention is a method for assessing capillary permeability to determine vascular lung injury without requiring the injection of radioactive material or requiring the sampling of blood. The method includes measuring impedance and ultrasonic velocity of blood flow through a lung. A hypertonic bolus is injected into the blood flow, and measurements of the blood flow are taken to determine the ultrasonic velocity and the electrical impedance of the blood. These measurements are used to calculate the capillary transport quantity, which is the product of the reflection coefficient for movement of fluid across the capillary barrier and the filtration coefficient. The measured value of the capillary transport quantity can then be compared to a conventional capillary transport quantity for healthy lungs, and one can determine injury by a significant decrease in the measured capillary transport quantity as compared to the standard measurements. Furthermore, a comparison of the osmotic transient graphs of the plotted indicator curves can serve to acknowledge lung vascular injury. Lung injury can be determined from the measured data when the point of osmotic equilibrium (where the indicator curve crosses the baseline) is significantly delayed as compared to the point of osmotic equilibrium plotted for a healthy lung.
BCL::Commons:: (BioChemistry Library Commons) is an object oriented C++ programming library. The library is designed to simulate biological molecules - proteins and peptides in particular - as well as small chemicals such as therapeutics. It comprises mathematical methods to evaluate the energy of these molecules in their natural environment. BCL::Jufo is the first publicly released BCL::Commons module.
Researchers in Vanderbilt University's STORM Lab have developed a novel actuation system that uses magnetic coupling to transmit mechanical power across a physical barrier. This technology is particularly suited for use in minimally invasive surgical procedures for manipulating surgical instruments across tissue barriers.
Bright minds at Vanderbilt University have unveiled a breakthrough technology that could bring sophisticated biomarker diagnostics to the developing world. The point-of-care diagnostic is designed to be used in the field; no specialized equipment, expertise, or white lab coats are required. The diagnostic is based upon the ingenous observation that evaporating liquid droplets leave behind a characteristic ring pattern, which may be familiar to our readers in the form of a coffee-ring stain.
Vanderbilt researchers have developed a low-cost, high sensitivity sensor based on a porous silicon (PSi) membrane waveguide. This sensor is designed to be a cost-effective alternative to conventional fiber optic and SPR sensors for both biosensing and chemical sensing applications.
Vanderbilt University researchers have developed an improved flexure based revolute joint which has better properties than a conventional flexure joint. Its split tube design enables a greater range of motion and withstands more load than conventional flexures while eliminating stick-slip and backlash behaviors.
Researchers in Vanderbilt University's STORM Lab have developed a wireless palpation device that uses magnetic coupling between two units to provide valuable feedback about tissue properties and potential abnormalities. The wireless capabilities of this technology make it ideally suited for minimally invasive surgery and natural orifice procedures, as the device does not require the use of a surgical port.
A new nanofiber composite membrane morphology and fabrication scheme has been developed at Vanderbilt University to be used for alkaline anion-exchange membrane fuel cells (AAEMFCs). This membrane has high hydroxyl ion conductivity, good mechanical properties, long term chemical stability and low water swelling. Additionally it is well suited for harsh conditions including high temperature and low humidity.
Researchers at Vanderbilt University have developed a novel material with high adsorbent capacity for toxic industrial chemicals of low concentrations in air. Due to the broad range of chemicals that can be adsorbed at these capacities, this technology will replace existing commercial and research grade materials serving as respirator adsorbents and single pass filters for a variety of military and non-military applications.
This invention combines the microfluidic and microelectronic devices and techniques required for the microminiaturization of cell culture and cell measurement systems to allow monitoring the response of populations of 1 to several hundred living cells. The instrument(s) allows for the detection of extracellular, membrane, and intracellular parameters; and the incorporation of closed-loop control techniques to continuously monitor the health of the cell and adjust the environmental and pharmacological parameters that control the cell.