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291 available technologies

KidSense Car Seat Safety System for Unattended Child Detection and Temperature Monitoring

A Vanderbilt engineering senior design team has developed a car seat safety attachment that detects if a child has been left unattended in a car seat and if the environment has become uncomfortably hot or cold. The system is designed with a graduated alarm system based on "alert states" that provides a combination of visual, tactile and audio alerts.

Colorectal Cancer Risk Screening Assay

The overall lifetime colorectal cancer risk for Americans is 5.1%, thus screening is recommended for those over the age of 50. Currently, colonoscopies are the standard for monitoring colon cancer development, but are invasive. Therefore, a need exists for a minimally-invasive test that could measure colon cancer risk. Ideally, such a test would offer a straightforward, personalized recommendation on how to substantially reduce colorectal cancer risk. Researchers at Vanderbilt University have identified a test that can characterize colorectal cancer risk and recommend a strategy for risk reduction. Importantly, this test requires only a blood sample and information about a person's diet.

Gene Signature Diagnostic to Measure LKB1 Loss and MEK Inhibitor Sensitivity

A Vanderbilt research group has discovered a diagnostic to identify patients with non-small cell lung cancer that would respond to MEK inhibitor therapies. This diagnostic indirectly measures loss of tumor suppressor activity by the protein LKB1. The traditional approach to determine MEK inhibitor sensitivity, which is measurement of LKB1 mutations, misses 50% of patients who would benefit from these drugs. This diagnostic measures expression of a small panel of genes to identify a larger population that is sensitive to MEK inhibition.

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