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283 available technologies

Robotic Platform for Transurethral Exploration and Intervention

This technology, developed in Vanderbilt University's Advanced Robotics and Mechanism Applications Laboratory, uses a minimally invasive telerobotic platform to perform transurethral procedures, such as transurethral resection. This robotic device provides high levels of precision and dexterity that improve patient outcomes in transurethral procedures.

Dispersed Detonation Nanodiamond Composites

Researchers at Vanderbilt University have developed a revolutionary method for incorporating nanodiamond particles into an existing polymer matrix. The resulting composite materials have greatly enhanced mechanical and chemical properties that can be tailored during this process.

Steerable Needles: A Better Turning Radius with Less Tissue Damage

A team of Vanderbilt engineers and surgeons have developed a new steerable needle that can make needle based biopsy and therapy delivery more accurate. A novel flexure-based tip design provides enhanced steerability while simultaneously minimizing tissue damage. The present device is useful for almost any needle-based procedure including biopsy, thermal ablation, brachytherapy, and drug delivery.

Non-Robotic Dexterous Laproscopic Instrument with a Wrist providing seven degrees of freedom

Inventors at Vanderbilt University have developed a non-robotic dexterous laparoscopic manipulator with a wrist providing seven-degrees-of-freedom. It provides an interface which intuitively maps motion of the surgeon's hands to the tool's "hands". The novel user interface approach provides a natural mapping of motion from the surgeon's hands to the instrument tips.

Algorithms for Compliant Insertion and Motion Control of Continuum Robots

This technology enables continuum robots (aka snake robots) to precisely navigate the intricate structures of deep anatomical passages during minimally invasive or natural orifice surgery. Collateral surgical damage is minimized by the force sensing capabilities of the algorithms used.

Assessment of Right Ventricular Function Using Contrast Echocardiography

Vanderbilt Medical Center researchers have developed a non-invasive and reproducible method of assessing right-ventricular function using contrast-echocardiography. The right-ventricular transit time (RVTT) measures the time needed for echocardiographic contrast to travel from the RV to the bifurcation of the main pulmonary artery. Coupled with the pulmonary transit time (PTT), the time needed for contrast to traverse the entire pulmonary circulation, RVTT is part of a family of diagnostic parameters that can report on RV-specific performance as well as the RV's function relative to that of the pulmonary circuit as a whole.

TagDock:an efficient rigid body molecular docking algorithm for three dimensional models of oligomeric biomolecular complexes with limited experimental restraint data

TagDock is an efficient rigid body molecular docking algorithm that generates three-dimensional models of oligomeric biomolecular complexes in instances where there is limited experimental restraint data to guide the docking calculations. Through distance difference analysis TagDock additionally recommends followup experiments to further discriminate divergent (score-degenerate) clusters of TagDock's initial solution models

GluN2B Floxed Mice (also called NR2B, glutamate receptor 2B)

Allows for targeted deletion of the GluN2B subunit of NMDA receptors in specific cells or at specific times during development, juvenile, or adult stages. C57BL6/J background

Ordered Mesoporous Silica- Metal Organic Composite Adsorbent

Vanderbilt researchers have developed a novel biphasic adsorbent material that is useful for the removal of contaminant molecules, including toxic light gases, from gases and liquids. This revolutionary material provides enhanced adsorption capacity and stability for a broad range of chemicals compared to conventional commercial and research grade adsorbent materials.

Collapsible Lightweight Portable Leg Holder for Ultrasound Guided Lateral Popliteal Block Procedures

A Vanderbilt team led by anesthesiologist Dr. Rajnish Gupta has developed a collapsible, lightweight and portable patient leg positioner for secure and stable leg positioning during ultrasound guided nerve block anesthetic procedures.

Metabolic Labeling Reagents for Chondroitin Sulfate

Dr. Patrick Page-McCaw has developed synthetic analogs of N-acetylgalactosamine, finally enabling researchers to track the biosynthesis of chondroitin sulfate along with other glycans. These stunning images demonstrate incorporation of these metabolic labeling reagents to track neurodevelopmental processes in a zebrafish model system. Notably, the metabolic label can be detected post vivo using a standard "click" chemistry reaction. Further, Dr. Page-McCaw has optimized a background reduction strategy to complement this technology by improving the signal-to-noise ratio.

Diamond Field-Emission Cathodes and Channeling Radiation System for High-Brightness X-ray Sources for Phase Contrast Soft Tissue Imaging

The technology disclosed is an electron gun system that comprises an array of gated field-emitting cathode tips having a diamond pyramid capable of producing an electron beam with exquisitely small emittance (N ~ 2 nm); an accelerator capable of accelerating the emitted electrons to relativistic energies (from ~ 3 Mev to~ 50MeV); and a focusing assembly capable of focusing the accelerated electrons into a focal spot on a diamond crystal to produce hard X-rays. Inventors have observed more than 10 mA average current from a single field-emitting tip with improved performance expected with changes to other system components. By using a single tip it may be possible to improve the transverse brightness of the electron beam by as much as six orders of magnitude, with a corresponding improvement of the spectral brilliance of the X-ray beam.

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