Available Technologies

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292 available technologies

FEATURED TECHNOLOGY

SERS Template Fabricated from Patterned Nanoporous Gold

Vanderbilt researchers have developed a technique that will amplify the Raman scattering signal from adsorbed molecules on a roughened metal surface to enable unique identification of the adsorbed molecules.
FEATURED TECHNOLOGY

Bright White Light Nanocrystals for LEDs

A research team lead by Professor Sandra Rosenthal at Vanderbilt University has developed nanocrystals (~2 nm diameter) that emit white light with very high quantum efficiency. This technology would be a viable cost effective candidate for commercial solid-state lighting applications, such as Light Emitting Diodes (LEDs). These nanocrystals were originally discovered by the same group in 2005; a recent breakthrough in post-treatment results in improving fluorescent quantum yield up to ~ 45%.
FEATURED TECHNOLOGY

Arbitrary Shape Selective Excitation Summed Spectroscopy (ASSESS)

Vanderbilt researchers have developed a novel single-voxel localization technique for Magnetic Resonance Spectroscopy (MRS), termed ASSESS (Arbitrary Shape Selective Excitation Summed Spectroscopy). ASSESS can measure spectra from regions of arbitrary shape allowing the user to customize the region of interest.
FEATURED TECHNOLOGY

System and Methods of Using Image-guidance for Placement of Cochlear Stimulator Devices, Drug Carrier Devices, or the Like

Vanderbilt inventors have developed and tested a device (C-in) and method that would shift the current invasive, risky surgical procedure of cochlear implantation to a less invasive outpatient procedure.
FEATURED TECHNOLOGY

PosiSeat™: Assured Seating of Threaded Surgical Components

Vanderbilt presents an intraoperative device for taking the guesswork out of whether or not a threaded component is securely affixed to bone. This device is an anchor driver that automatically releases upon proper seating of the anchor on the bone of interest.
FEATURED TECHNOLOGY

MultiUse Multimodal Imaging Chelates

PK11195 is a high-affinity ligand of the peripheral benzodiazepine receptor (PBR). By linking lanthanide chelates to the PK11195 targeting moiety, Vanderbilt researchers have generated a range of PBR-targeted imaging probes capable of visualizing a number of disease states at cellular levels using a variety of imaging modalities (fl uorescence, PET and SPECT, MRI, electron microscopy).
FEATURED TECHNOLOGY

Device for Hernia Mesh/Tissue Graft Positioning and Placement

Simple device to assist in selection of appropriate sized mesh/tissue graft for abdominal wall hernia repair. This device will then be utilized to "stretch" the material flat removing redundancies/folds. Once "flattened" the material can be pulled to the abdominal wall without the need for multiple instruments. The mesh/tissue graft can then be appropriately positioned over the defect to assure adequate material overlap. Once positioned the material is fixed in place with traditional techniques.The device can also be used in a similar fashion via a natural orifice transluminal endoscopic surgery for anterior abdominal wall defects.
FEATURED TECHNOLOGY

Cuffed Inner Cannula and Flexible Outer Cannula Tracheostomy Tube

This new tracheostomy tube design prevents the need for decannulation when changing from a cuffed to cuffless (or vice versa) tracheostomy. It also enables a comfortable and fit in patients with both large and small neck diameters. The tube enhances patient safety by maintaining the airway at all times when downsizing or upsizing.
FEATURED TECHNOLOGY

Intervertebral Disc Replacement

An implantable intervertebral disc prosthesis that comprises a disc member having an upper surface, a lower surface, and a perimeter surface. The disc includes an axis at least one slit defined in the perimeter surface; the slit being of sufficient depth and thickness to provide flexure. The slit terminates in a perimeter opening larger than the slit thickness. The perimeter opening (i.e., hole) acts as a pivot point and relieves stress. The disc prosthesis optionally comprises a cavity with an upper seat defined on the lower surface, a lower disc having an upper and lower surface and a lower seat defined on the upper surface, and a support ball. The support ball engages the seat on the upper disc and the seat on the lower disc.
FEATURED TECHNOLOGY

Patent Ductus Arteriosus Stent

Vanderbilt researchers have created a low-cost, removable Patent Ductus Arteriosus (PDA) stent for pediatric patients. There is currently no commercially available pediatric PDA stent, but it is estimated that over 3,000 babies are born each year in the United States with cyanotic heart disease; a significant fraction of whom can benefit from temporary placement of the PDA stent described here.
FEATURED TECHNOLOGY

Peptide and Protein Fragmentation by Lysine Residue Originated Reactions

A method of modifying protein samples that comprises combining the sample with a peroxycarbonate solution and inserting the sample into a mass spectrometer. The present invention also includes methods of N-terminus characterization.
FEATURED TECHNOLOGY

Human Monoclonal Antibodies to Infectious Diseases

Using human B cell hybridoma creation, and antibody engineering technologies, Dr. James E Crowe Jr.'s laboratory has developed an array of antibodies from full length human antibodies to Fab fragments and diabodies. Many of these antibodies are ready for a cooperate partner who can further develop these antibodies into biologic herapeutics. The table below is a sample of the antibodies they are currently researching and have available. In addition to these areas of research, Dr. Crowe is actively seeking collaborative opportunities to identify new interesting targets for future antibody engineering projects.
FEATURED TECHNOLOGY

Molecular Profiles for Subtyping Triple Negative Breast Cancer

Personalized medicine is at the forefront of medical news and specialized diagnostics that can align patients with the correct treatment are the key to this type of medicine. Jennifer Pietenpol and colleagues have performed extensive research and discovered that triple negative breast cancer (TNBC) is a heterogeneous disease with at least six subtypes. These subtypes have differing biological behaviors and sensitivities to known therapeutics. Diagnostic assays will help guide personalized and more effective therapy.

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2012 Highlights

A motion graphic video describing operational improvements and successes of FY2012. Click here for a full PDF report.