Available Technologies

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295 available technologies

Polar Liquid Crystals with High Dielectric Anisotropy

Vanderbilt inventors have developed a new class of liquid crystals with high dielectric anisotropy. A new class of liquid crystals containing boron in their structure has been developed with high dielectric anisotropy, which results in low threshold voltages.

Magnetically Attachable Polydimethylsiloxane Stencils (MAtS)

Vanderbilt researchers have developed a unique system for patterning cells or proteins in cell culture environments using magnetically attachable stencils (MAtS) secured onto a culture surface by applying transbase magnets.

Rotary planar peristaltic micropump (RPPM) and Rotary Planar Valve (RPV) for microfluidic systems

A research team led by Professor John Wikswo of Vanderbilt University has developed a low-cost, small-volume, metering peristaltic micro pumps and microvalves. They can be either utilized as a stand-alone device, or incorporated into microfluidic subsystems for research instruments or miniaturized point-of-care instruments, Lab on a Chip devices, and disposable fluid delivery cartridges. The key advantage of this pump is that it can deliver flow rates as low as a few hundred nL/min to tens of µL/min against pressure heads as high as 20 psi, at approximately 1/10th the cost of stand-alone commercial syringe and peristaltic pumps. The RPV can implement complicated fluid control protocols and fluidic mixing without bulky pneumatic controllers. Both the RPPM and RPV can be readily optimized for particular applications.

Bright White Light Nanocrystals for LEDs

A research team lead by Professor Sandra Rosenthal at Vanderbilt University has developed nanocrystals (~2 nm diameter) that emit white light with very high quantum efficiency. This technology would be a viable cost effective candidate for commercial solid-state lighting applications, such as Light Emitting Diodes (LEDs). These nanocrystals were originally discovered by the same group in 2005; a recent breakthrough in post-treatment results in improving fluorescent quantum yield up to ~ 45%.

Arbitrary Shape Selective Excitation Summed Spectroscopy (ASSESS)

Vanderbilt researchers have developed a novel single-voxel localization technique for Magnetic Resonance Spectroscopy (MRS), termed ASSESS (Arbitrary Shape Selective Excitation Summed Spectroscopy). ASSESS can measure spectra from regions of arbitrary shape allowing the user to customize the region of interest.

System and Methods of Using Image-guidance for Placement of Cochlear Stimulator Devices, Drug Carrier Devices, or the Like

Vanderbilt inventors have developed and tested a device (C-in) and method that would shift the current invasive, risky surgical procedure of cochlear implantation to a less invasive outpatient procedure.

PosiSeat™: Assured Seating of Threaded Surgical Components

Vanderbilt presents an intraoperative device for taking the guesswork out of whether or not a threaded component is securely affixed to bone. This device is an anchor driver that automatically releases upon proper seating of the anchor on the bone of interest.

MultiUse Multimodal Imaging Chelates

PK11195 is a high-affinity ligand of the peripheral benzodiazepine receptor (PBR). By linking lanthanide chelates to the PK11195 targeting moiety, Vanderbilt researchers have generated a range of PBR-targeted imaging probes capable of visualizing a number of disease states at cellular levels using a variety of imaging modalities (fl uorescence, PET and SPECT, MRI, electron microscopy).

Device for Hernia Mesh/Tissue Graft Positioning and Placement

Simple device to assist in selection of appropriate sized mesh/tissue graft for abdominal wall hernia repair. This device will then be utilized to "stretch" the material flat removing redundancies/folds. Once "flattened" the material can be pulled to the abdominal wall without the need for multiple instruments. The mesh/tissue graft can then be appropriately positioned over the defect to assure adequate material overlap. Once positioned the material is fixed in place with traditional techniques.The device can also be used in a similar fashion via a natural orifice transluminal endoscopic surgery for anterior abdominal wall defects.

Cuffed Inner Cannula and Flexible Outer Cannula Tracheostomy Tube

This new tracheostomy tube design prevents the need for decannulation when changing from a cuffed to cuffless (or vice versa) tracheostomy. It also enables a comfortable and fit in patients with both large and small neck diameters. The tube enhances patient safety by maintaining the airway at all times when downsizing or upsizing.

Intervertebral Disc Replacement

An implantable intervertebral disc prosthesis that comprises a disc member having an upper surface, a lower surface, and a perimeter surface. The disc includes an axis at least one slit defined in the perimeter surface; the slit being of sufficient depth and thickness to provide flexure. The slit terminates in a perimeter opening larger than the slit thickness. The perimeter opening (i.e., hole) acts as a pivot point and relieves stress. The disc prosthesis optionally comprises a cavity with an upper seat defined on the lower surface, a lower disc having an upper and lower surface and a lower seat defined on the upper surface, and a support ball. The support ball engages the seat on the upper disc and the seat on the lower disc.

Patent Ductus Arteriosus Stent

Vanderbilt researchers have created a low-cost, removable Patent Ductus Arteriosus (PDA) stent for pediatric patients. There is currently no commercially available pediatric PDA stent, but it is estimated that over 3,000 babies are born each year in the United States with cyanotic heart disease; a significant fraction of whom can benefit from temporary placement of the PDA stent described here.

Peptide and Protein Fragmentation by Lysine Residue Originated Reactions

A method of modifying protein samples that comprises combining the sample with a peroxycarbonate solution and inserting the sample into a mass spectrometer. The present invention also includes methods of N-terminus characterization.

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